Results 221 to 230 of about 1,723,808 (348)

Enhancing biological SAXS by solvent contrast variation: Effect on structural stability and enzymatic activity

Viviam M. da Silva, Aurélien Thureau, Dominique Madern, Bruno Franzetti, Wanius García, Javier Pérez, Éric Girard, Frank Gabel   +7 more
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Assessing the chemical profile and biological potentials of Tamarix smyrnensis flower extracts using different solvents by in vitro, in silico, and network methodologies

Erdi Can Aytar, Emine İncilay Torunoğlu, Abidin Gümrükçüoğlu, Saleh Alfarraj, Alper Durmaz, Mika Sillanpää   +5 more
openalex   +1 more source

Solvent-free ionic liquids as in situ probes for assessing the effect of ion size on the performance of electrical double layer capacitors

, 2006
Conchi O. Ania, Juliusz Pernak, Filip Stefaniak, Encarnación Raymundo‐Piñero, François Béguin   +4 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A quantum chemical dataset of interacting molecular pairs for chemical reaction studies. [PDF]

J Cheminform
Jang S, Na GS.
europepmc   +1 more source

Larvicidal and phytochemical properties of <i>Callistemon rigidus</i> R. Br. (Myrtaceae) leaf solvent extracts against three vector mosquitoes

, 2014
Danga Yinyang Simon Pierre, Charles Okechukwu Esimone, Nukenine Elias Nchiwan   +2 more
openalex   +1 more source

Dataset of: Solvent-Free Processed Polymer Electrolyte for Li-Metal Batteries

Otaegui, Laida, Blanco, June, Al Sammarraie Shakir, Mustafa, Yuriychuk, Nastasiya, Fraile-Insagurbe, David, Boaretto, Nicola   +5 more
openalex   +1 more source

Capturing the Role of Explicit Solvent in the Dimerization of Ru^V(bda) Water Oxidation Catalysts

, 2017
Shaoqi Zhan, Daniel Mårtensson, Miha Purg, Shina Caroline Lynn Kamerlin, Mårten S. G. Ahlquist   +4 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source