Results 71 to 80 of about 1,982,889 (334)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Transient cavities and the excess chemical potentials of hard-spheroid solutes in dipolar hard sphere solvents [PDF]

open access: yes, 2005
Monte Carlo computer simulations are used to study transient cavities and the solvation of hard-spheroid solutes in dipolar hard sphere solvents. The probability distribution of spheroidal cavities in the solvent is shown to be well described by a ...
Allen M. P.   +4 more
core   +2 more sources

Purification of ethanol for highly sensitive self-assembly experiments

open access: yesBeilstein Journal of Nanotechnology, 2014
Ethanol is the preferred solvent for the formation of self-assembled monolayers (SAMs) of thiolates on gold. By applying a thin film sensor system, we could demonstrate that even the best commercial qualities of ethanol contain surface-active ...
Kathrin Barbe   +3 more
doaj   +1 more source

Effect of Harvest Age and Solvents on the Phenolic Content of Eucheuma cot-tonii Extract Eucheuma cot-tonii Extra

open access: yesMakara Journal of Science, 2020
Bioactive compounds in Eucheuma cottonii include phenols or polyphenols with antioxidant, antibacterial, and antiviral properties. Seaweed quality, including phenolic content, is highly determined by several factors, including the growth location ...
Ninik Purbosari   +3 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Effect of Recycle Solvent Hydrotreatment on Oil Yield of Direct Coal Liquefaction

open access: yesEnergies, 2015
Effects of the recycle solvent hydrotreatment on oil yield of direct coal liquefaction were carried out in the 0.18 t/day direct coal liquefaction bench support unit of National Engineering Laboratory for Direct Coal Liquefaction (China).
Shansong Gao, Dexiang Zhang, Kejian Li
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hydration and anomalous solubility of the Bell-Lavis model as solvent [PDF]

open access: yes, 2012
We address the investigation of the solvation properties of the minimal orientational model for water, originally proposed by Bell and Lavis. The model presents two liquid phases separated by a critical line.
Carlos E. Fiore   +4 more
core   +2 more sources

Effect of solvent on the energy storage property of poly(vinylidene fluoride-hexafluoropropylene)

open access: yesMaterials Research Express, 2020
The application prospects of dielectric materials such as poly(vinylidene fluoride) (PVDF) based polymers in the field of energy storage have stimulated extensive research.
Fujia Chen   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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