Results 151 to 160 of about 1,669,284 (296)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ultrasound-assisted deep eutectic solvent extraction of tyrosinase inhibitors from lotus seed peel powder. [PDF]

open access: yesUltrason Sonochem
Zhang C   +7 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Solvent Extr. Ion Exch.

open access: yes, 1994
The cobalt(LI) extraction kinetics and mechanism with EHEHPA (2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester) were investigated by an improved constant interfacial area stirred cell.
ZHU, T, CHEN, CQ
core  

Optimization of Phenolic Compounds Recovery from Pistachio Hull Using Accelerated Solvent Extraction. [PDF]

open access: yesAntioxidants (Basel)
Paniagua-García AI   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Development of solvent extraction processes for the H.T.G.C.R. fuel cycle, Part 3 - chemical data for the extraction of actinides and fission products from aqueous beryllium sulphate solutions using amines.

open access: yes, 1968
Chemical data are presented for the actinides (uranium, plutonium and thorium), the fission products (cerium, zirconium, niobium and ruthenium) and beryllium in the extraction of these from beryllium sulphate solutions by amines, in particular Primene ...
Fardy, JJ, Farrell, MS
core  

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