Results 191 to 200 of about 2,653,426 (391)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

A thermodynamic study of relative extractability of ethanol to blood simulating solvent in extractables and leachables analysis of medical devices by Abraham’s Solvation Parameter Model

open access: yesJournal of Chromatography Open
A thermodynamic study of over-extraction of blood contacting medical devices by ethanol to ethanol/water binary cosolvent mixture (50/50, v/v), as a blood simulating solvent, in chemical analysis of medical devices is evaluated by Abraham’s solvation ...
Jianwei Li
doaj  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Binary solvent extraction of intracellular lipids from Rhodotorula toruloides for cell recycling. [PDF]

open access: yesBiotechnol Biofuels Bioprod
Song J   +5 more
europepmc   +1 more source

Solvent Extraction of 152,154Eu and 241Am by Di-n-butyl Phosphate (DBP) in Different Organic Solvents. [PDF]

open access: bronze, 1960
David Dyrssen   +4 more
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

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