Results 231 to 240 of about 644,240 (320)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Efficient removal of lipophilic compounds from sewage sludge: Comparative evaluation of solvent extraction techniques. [PDF]

Heliyon
Ekka B, Mierina I, Zarina R, Mezule L.
europepmc   +1 more source

Lignin with controlled structural properties by N-heterocycle-based deep eutectic solvent extraction. [PDF]

Proc Natl Acad Sci U S A, 2023
Lin KT, Wang C, Guo MF, Aprà E, Ma R, Ragauskas AJ, Zhang X.   +6 more
europepmc   +1 more source

Studies on Solvent Extraction Using Radioactive Isotope. VII. Solvent Extraction of Antimony?Hydrochloric Acid System

, 1960
Nobuo N. Noda
openalex   +2 more sources

The roles and applications of extracellular vesicles in cancer

Molecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Protocol for extracting oil from Ghana shea nuts using solvent extraction. [PDF]

STAR Protoc
Alale EM, Tulashie SK, Baidoo EB, Addai CM.   +3 more
europepmc   +1 more source

Conversion of Lithium Chloride into Lithium Hydroxide by Solvent Extraction. [PDF]

J Sustain Metall, 2023
Nguyen VT, Deferm C, Caytan W, Riaño S, Jones PT, Binnemans K.   +5 more
europepmc   +1 more source

SOLUBILITY OF ZIRCONIUM DIBUTYL PHOSPHATE IN SOLVENT EXTRACTION SOLUTIONS

, 1960
W. Jr. Davis, Halbert Carmichael
openalex   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Synergistic Solvent Extraction of Lanthanoids with Traditional Ligands (4-Acylpyrazolone and Bidentate Nitrogen Bases) in a Nontraditional Diluent Confirmed by Slope Analysis and NMR. [PDF]

Molecules
Atanassova M, Todorova N, Simova S.
europepmc   +1 more source