Results 221 to 230 of about 1,863,026 (296)

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Fabio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Matrix-Aware LC-MS/MS Quantification of Cyhexatin in Chemically Complex Herbal Matrices Using DOE-Assisted Extraction Optimization. [PDF]

ACS Omega
Kim JY, Lee SM, Lee WJ, Ha YR, Lee J, Lee OJ, Kim HM, Kim H, Lee DK, Han SB, Wood TD, Choi YS.   +11 more
europepmc   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

Development and validation of dispersive liquid-liquid microextraction coupled with LC-MS/MS for plasma 5-hydroxyindoleacetic acid quantification with application as a biomarker in major depressive disorder. [PDF]

Sci Rep
Alaqel SI, Abd Al Maksoud AA, Aljameeli AM, Alaradi MM, Aldawsari MF, Serag A, Almalki AH.   +6 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Recovery of Hydroxytyrosol from Olive Pomace: Extraction, Purification, Bioactivity, and Bioavailability. [PDF]

Foods
He J, Li T, Hai G, Zhang C.
europepmc   +1 more source

Optimization of Onion Peel Bioactive Compounds Using Eco-Friendly Natural Deep Eutectic Solvent Based Ultrasound-Assisted Extraction. [PDF]

Food Sci Nutr
Rasool IFU, Arshad MU, Imran A, Siddiqa A, Bugingo E.   +4 more
europepmc   +1 more source

A critical review of absorption-driven CO₂ capture and techno-economic feasibility. [PDF]

RSC Adv
Almutairi G, Ahmed Ali FA, Al-Zahrani SA, Alwadai N, Ganesan S, Alsaleh M, Asiri M, Alnassar S, Kumar TV, Padmanabhan S, Saravanan P, Jayakumar S, Kavitha C.   +12 more
europepmc   +1 more source