Results 131 to 140 of about 1,075,486 (337)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A Grape-Derived Solvent for the Recovery of Phenolic Compounds from Food Waste By-Products Using Ultrasonic-Assisted and Overnight Extraction

Molecules
This present study aimed to investigate the recovery of polyphenols from red onion peel (OPP) and pomace of Merlot (MWP) and Syrah (SWP) grape varieties, using a common biphasic solvent (70/30 ethanol/water) and a new biphasic and eco-friendly solvent ...
Dimitrios G. Lazaridis, Vassilios K. Karabagias, Nikolaos D. Andritsos, Aris E. Giannakas, Ioannis K. Karabagias   +4 more
doaj   +1 more source

An integrated process by ultrasonic enhancement in the deep eutectic solvents system for extraction and separation of chlorogenic acid from Eucommia ulmoides leaves

, 2023
Yue Meng, Xiaoyu Sui, Xu Pan, Ying Yang, Huimin Sui, Tao Xu, Honglian Zhang, Tingting Liu, Jicheng Liu, Pengling Ge   +9 more
openalex   +1 more source

A Simple Work-Up-free, Solvent-free Approach to Novel Amino Acid Linked 1,4-Disubstituted 1,2,3-Triazoles as Potent Antituberculosis Agents [PDF]

, 2020
Anirban Garg, Debajit Borah, Priyanka Trivedi, Dipshikha Gogoi, Amrita Kashyap Chaliha, Abdul Aziz Ali, Dipak Chetia, Vinita Chaturvedi, Diganta Sarma   +8 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Formation of Racemic Phases of Amino Acids by Liquid-Assisted Resonant Acoustic Mixing Monitored by Solid-State NMR Spectroscopy

Molecules
Mechanochemistry has become a fundamental method in various sciences including biology and chemistry. Despite its popularity, the mechanisms behind mechanochemically induced reactions are not very well understood.
Leeroy Hendrickx, Calogero Quaranta, Emilian Fuchs, Maksim Plekhanov, Mirijam Zobel, Carsten Bolm, Thomas Wiegand   +6 more
doaj   +1 more source

Zero Liquid Discharge of Ultrahigh-Salinity Brines with Temperature Swing Solvent Extraction

, 2020
Chanhee Boo, Ian H. Billinge, Xi Chen, Kinnari M. Shah, Ngai Yin Yip   +4 more
openalex   +1 more source

Impact of Eutectic Solvents Utilization in the Microwave Assisted Extraction of Proanthocyanidins from Grape Pomace [PDF]

, 2021
Rodrigo T. Neto, Sónia A.O. Santos, Joana Oliveira, Armando J. D. Silvestre   +3 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source