Results 71 to 80 of about 1,287,454 (361)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Development of a HPLC protocol to characterize flexible PU foams in support of advanced recycling

open access: yesPolymer Testing
We present a novel High-Performance Liquid Chromatography (HPLC) protocol to characterize flexible polyurethane (PU) foams, aiming to enhance chemical recycling processes.
Jonas Cassimon   +9 more
doaj  

Investigation of Extraction Yields of Exfoliated Graphene in Deionized Water from Organic Solvents

open access: yesInternational Journal of Technology, 2019
Organic solvent is suitable for the exfoliation of graphene. However, for the end application of exfoliated graphene it needs to extract and re-disperse to the required media.
A Arifutzzaman   +4 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Could fibrinogen and hsCRP be useful for assessing personal risk in workers exposed to a mixture of ultrafine particles and organic solvents?

open access: yesRomanian Journal of Laboratory Medicine, 2018
Purpose: Our study focuses on elucidating if two common inflammatory biomarkers, easily performed in any laboratory - high-sensitivity C-reactive protein (hsCRP), as well as fibrinogen - could be used to assess the personal health risk of workers exposed
Voidazan Septimiu   +6 more
doaj   +1 more source

Evaluation of the effectiveness of three different solvents in dissolving gutta-percha and GuttaFlow: in vitro

open access: yesActa Odontologica Turcica, 2017
Objective: The aim of this study was the comparative evaluation of the effectiveness of orange oil, turpentine oil, and chloroform in dissolving gutta-percha and GuttaFlow discs.
Evren Sarıyılmaz, Cangül Keskin
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

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