Results 121 to 130 of about 144,411 (289)

Neuromorphic Hardware Materials for Intelligent Artificial Perception and Multimodal Fusion: From Sensing to Cognition

Interdisciplinary Materials, EarlyView.
Neuromorphic hardware enables the integration of sensing, memory, and computing for intelligent artificial perception. Recent advances in multimodal fusion further highlight its potential for embodied intelligence and next‐generation human–machine interfaces.
Yixin Zhu, Yuqing Hu, Changjin Wan, Qing Wan   +3 more
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

Evaluación de la Dermatoscopia en el diagnóstico de las queratosis seborreicas

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2000
La dermatoscopia ha demostrado que aumenta la agudeza del diagnóstico clínico del melanoma maligno y de otras lesiones pigmentadas de la piel.
Ana Patricia Jaramillo Ramírez, Juan Guillermo Hoyos Gaviria, Susana Restrepo Gutiérrez   +2 more
doaj  

Humanism in the Age of Hyperreality: A Speculative Critique of AI Therapybots and the Neoliberal Commodification of Human Beings

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This article examines the future place of humanistic counseling, assuming the successful mass deployment of artificial intelligence therapy chatbots (AITCs). We systematically identify the limitations of AITCs through the lens of Jean Baudrillard's view on simulacra and hyperreality and identify five collective psychosocial consequences of ...
Brett. D. Wilkinson, Andrew M. Brown
wiley   +1 more source

Development and validation of the new French ORALQUEST scale for evaluating feeding difficulties in young children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Feeding difficulties are common in children with and without somatic conditions. Our objective was to develop a parent‐report questionnaire (ORALQUEST) designed to be administered by a professional and to assess feeding difficulties in children aged 9 months to 6 years. Methods The questionnaire explores four domains: eating behavior,
Béatrice Thouvenin, Redha Ould‐Ammar, Lisa Ouss, Pascale Gavelle, Giulia Disnan, Aurélie Royer, Nancy Vegas, Catherine du Fraysseix, Pauline Adnot, Valeria Barbieri, Christine Hassler, Caroline Elie, Caroline Barry, Véronique Abadie   +13 more
wiley   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

Dependence of the Extra‐Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter

Magnetic Resonance in Medicine, EarlyView.
Purpose The dependence of the long‐time (tortuosity) limit of the extra‐cellular diffusivity on the intra‐cellular volume fraction is of fundamental importance for microstructure modeling. While such dependencies have been explored for the white matter, the tortuosity limit in gray matter is unknown due to complex cell composition and geometry. Here we
Hong‐Hsi Lee, Ali Abdollahzadeh, Hansol Lee, Ricardo Coronado‐Leija, Els Fieremans, Susie Y. Huang, Dmitry S. Novikov   +6 more
wiley   +1 more source

Comparative Systematic Analysis of Gray Matter Biophysical Models on a Public Dataset

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Biophysical models of diffusion tailored to characterize gray matter (GM) microstructure are gaining traction in the neuroimaging community. NEXI, SMEX, SANDI, and SANDIX represent recent efforts to account for different microstructural features, such as soma contributions and inter‐compartment exchange, in the diffusion MRI (dMRI ...
Santiago Mezzano, Quentin Uhl, Tommaso Pavan, Jasmine Nguyen‐Duc, Hansol Lee, Susie Huang, Ileana Jelescu   +6 more
wiley   +1 more source

Brain Clearance of Contrast Agent in Intravenous DCE‐MRI Is Measurable and Cannot Be Explained by Clearance Across the BBB Alone

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data from people with Parkinson's disease, post ...
Martin Kozár, Ioana‐Emilia Mosneag, Sarah Al‐Bachari, Igor Chernyavsky, Geoff J. M. Parker, Hervé Boutin, Laura M. Parkes, Ingo Schiessl, Ben R. Dickie   +8 more
wiley   +1 more source