Results 221 to 230 of about 144,411 (289)

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong   +18 more
wiley   +1 more source

Amacrine cell inputs to OFF midget ganglion cells in macaque retina

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak   +8 more
wiley   +1 more source

Tonotopically distinct OFF responses arise in the mouse auditory midbrain following sideband suppression

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sounds of different frequencies elicit spatially distinct patterns of neural activity within the inferior colliculus aligned to the tonotopic organization of afferent projections. Sound‐evoked neural responses can be visualized in awake mice that express fluorescent Ca2+ sensors.
Patrick D. Parker   +2 more
wiley   +1 more source

Expression of GPR34 in microglia remains stable in human Alzheimer's disease. [PDF]

open access: yesActa Neuropathol
Seiffer S   +9 more
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

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