Results 41 to 50 of about 144,411 (289)

The Space Omics and Medical Atlas (SOMA) and international astronaut biobank

Nature
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space1–6.
Eliah G. Overbey, Jangkeun Kim, B. Tierney, Jiwoon Park, Nadia Houerbi, Alexander G. Lucaci, Sebastian Garcia Medina, N. Damle, D. Najjar, K. Grigorev, Evan E. Afshin, K. Ryon, K. Sienkiewicz, L. Patras, Remi V. Klotz, Veronica Ortiz, M. Mackay, A. Schweickart, Christopher R. Chin, M. Sierra, Matías Valenzuela, E. Dantas, Theodore M. Nelson, Egle Cekanaviciute, Gabriel Deards, J. Foox, S. Narayanan, Caleb M. Schmidt, Michael A Schmidt, J. Schmidt, Sean Mullane, S. S. Tigchelaar, Steven Levitte, Craig D. Westover, Chandrima Bhattacharya, Serena Lucotti, J. Wain Hirschberg, J. Proszynski, Marissa Burke, Ashley S. Kleinman, D. Butler, C. Loy, Omary Mzava, J. Lenz, Doru Paul, C. Mozsary, Lauren M. Sanders, Lynn Taylor, Chintan O. Patel, Sharib A. Khan, Mir Suhail Mohamad, S. G. Byhaqui, Burhan Aslam, Aaron S. Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan Benz, Asim Siddiqui, Daniel Hornburg, Kelly Blease, Juan Moreno, Andrew M. Boddicker, Junhua Zhao, Bryan R. Lajoie, Ryan T. Scott, R. Gilbert, San-huei Lai Polo, Andrew Altomare, S. Kruglyak, Shawn Levy, Ishara S. Ariyapala, Joanne C. Beer, Bingqing Zhang, Briana M. Hudson, Aric Rininger, Sarah E. Church, Afshin Beheshti, George M. Church, Scott M. Smith, Brian E. Crucian, S. Zwart, Irina R Matei, D. Lyden, Francine E. Garrett-Bakelman, J. Krumsiek, Qiuying Chen, Dawson Miller, Joe Shuga, Stephen R. Williams, Corey M. Nemec, Guy Trudel, M. Pelchat, O. Laneuville, Iwijn De Vlaminck, Steven S. Gross, Kelly L. Bolton, Susan M. Bailey, Richard D. Granstein, D. Furman, Ari M. Melnick, S. Costes, B. Shirah, Min Yu, Anil S. Menon, Jaime Mateus, Cem Meydan, Christopher E. Mason   +108 more
semanticscholar   +1 more source

Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity

Cell Reports, 2019
SUMMARY Neurons face the challenge of maintaining cellular homeostasis through lysosomal degradation. While enzymatically active degradative lysosomes are enriched in the soma, their axonal trafficking and positioning and impact on axonal physiology ...
T. Farfel-Becker, Joseph C Roney, Xiu-Tang Cheng, Sunan Li, Sean R. Cuddy, Zu-Hang Sheng   +5 more
semanticscholar   +1 more source

The Neonatal Assessment Manual scorE: A Reliability Study on Hospitalized Neonates

Frontiers in Pediatrics, 2021
Despite clinical improvements in neonatal intensive care units (NICUs), prematurity keeps causing several comorbidities. To enhance the management of such conditions, in previous studies we devised the Neonatal Assessment Manual scorE (NAME) model, a ...
Andrea Manzotti, Andrea Manzotti, Andrea Manzotti, Francesco Cerritelli, Erica Lombardi, Erica Lombardi, Simona La Rocca, Simona La Rocca, Pamela Biasi, Pamela Biasi, Marco Chiera, Matteo Galli, Matteo Galli, Gianluca Lista   +13 more
doaj   +1 more source

Embracing First-Person Perspectives in Soma-Based Design

Informatics, 2018
A set of prominent designers embarked on a research journey to explore aesthetics in movement-based design.
Kristina Höök, Baptiste Caramiaux, Cumhur Erkut, Jodi Forlizzi, Nassrin Hajinejad, Michaele Haller, Carolin Hummels, Katherine Isbister, M. Jonsson, G. Khut, L. Loke, D. Lottridge, Patrizia Marti, ID Edward, Melcer, F. Müller, M. Petersen, Thecla Schiphorst, Elena M á rquez Segura, Anna Ståhl, Dag Svanæs, Jakob Tholander, Helena Tobiasson   +22 more
semanticscholar   +1 more source

The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in Aspergillus fumigatus

mBio, 2020
The cell wall is essential for fungal viability and is absent from human hosts; thus, drugs disrupting cell wall biosynthesis have gained more attention.
Yuan Chen, F. Le Mauff, Yan Wang, Ruiyang Lu, D. Sheppard, Ling Lu, Shizhu Zhang   +6 more
semanticscholar   +1 more source

Terminy: to soma, he sarks w komentarzu Dydyma Aleksandryjskiego do Księgi Rodzaju

Vox Patrum, 2000
Hoc in articulo de significatu vocabuiorum to soma, he sarks in anthropołogia Didymi Alexandrini in eiusdem Commentario in Genesin proposita tractatur.
Rafał Nakonieczny
doaj   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma

Journal of Anaesthesiology Clinical Pharmacology, 2016
Soma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic ...
Gunchan Paul, Gautam L Parshotam, Rajneesh Garg   +2 more
doaj   +1 more source

Cancer Screening, Surrogates of Survival, and the Soma.

Cancer Cell, 2020
Screening leads to meaningful reductions in deaths from cancers. However, reductions in all-cause mortality (ACM) are harder to demonstrate. Failure to demonstrate ACM benefit should not diminish advances in cancer screening.
J. DeGregori, P. Pharoah, P. Sasieni, C. Swanton   +3 more
semanticscholar   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source