Results 131 to 140 of about 195,697 (244)

Conserved Gene Expression Plasticity in Development Is More Pervasive Than Expression Divergence Between Species of Caenorhabditis Nematodes. [PDF]

Evol Dev
Viswanath A, Fusca DD, Calarco JA, Cutter AD.   +3 more
europepmc   +1 more source

Serendipitous compound action potential oscillations reveal glycolytic astrocyte and oxidative axon interstitial K+ buffering in central white matter

Experimental Physiology, EarlyView.
Abstract The principal processes that govern interstitial K+ ([K+]o) buffering in mouse optic nerve (MON), a central white matter tract, either directly consume energy (Na+–K+‐ATPase) or use transmembrane ion gradients created by energy‐dependent pumps to enable the K+ fluxes that maintain a stable [K+]o, and thus ready availability of utilisable ...
Amy J. Hopper, Angus M. Brown
wiley   +1 more source

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

Experimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela, Anuja R. Bony, Sonia Garcia‐Caraballo, David J. Adams, Stuart M. Brierley   +4 more
wiley   +1 more source

Early and progressive retinal microglial changes in APP^NL-F/NL-F mouse model of Alzheimer's disease revealed by an automated image analysis software. [PDF]

Front Aging Neurosci
Sánchez-Puebla L, López-Cuenca I, Sánchez-Puebla MA, Granados A, Ramírez AI, Llorens J, Saido TC, Saito T, Nieto-Vaquero C, Moro MA, Moreno V, Ramírez JM, de Hoz R.   +12 more
europepmc   +1 more source

Modulation of slow and fast oscillations by direct current stimulation in the cerebral cortex in vitro

The Journal of Physiology, EarlyView.
Abstract figure legend Direct‐current (DC) electric fields modulate spontaneous slow oscillations in cerebral cortex slices in vitro. Schematic of the in vitro preparation (upper panels). Spontaneous slow oscillations (SO; <1 Hz) consisting of alternating Up (active) and Down (silent) states were observed under control conditions.
Mattia D'Andola, Julia F. Weinert, Joana Covelo, Maurizio Mattia, Maria V. Sanchez‐Vives   +4 more
wiley   +1 more source

Tracking the morphological evolution of neuronal dendrites by first-passage analysis. [PDF]

Biophys J
Kreten FH, Niemeyer BA, Santen L, Shaebani R.   +3 more
europepmc   +1 more source

Ultrastructure of astrocytes using volume electron microscopy: A scoping review

The Journal of Physiology, EarlyView.
Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini, Maria Fernanda Veloz Castillo, Francesco Biancardi, Ferdinando Di Cunto, Pierre J. Magistretti, Alessandro Vercelli, Marco Agus, Corrado Calì   +7 more
wiley   +1 more source

Regression of a Cardiac Calcified Amorphous Tumor Under Antiplatelet Therapy in a Patient With Ischemic Stroke: A Case Report and Literature Review. [PDF]

Cureus
Matsueda S, Makino R, Nagano Y, Higa N, Tanaka S, Yamahata H, Hanaya R.   +6 more
europepmc   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury. [PDF]

Cell Death Discov
Marola OJ, Syc-Mazurek SB, Yablonski SER, Shrager PG, John SWM, Libby RT.   +5 more
europepmc   +1 more source