Results 71 to 80 of about 41,599 (347)

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source

Enaminone Modulators of Extrasynaptic α4β3δ γ-Aminobutyric AcidA Receptors Reverse Electrographic Status Epilepticus in the Rat After Acute Organophosphorus Poisoning

Frontiers in Pharmacology, 2019
Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic γ-aminobutyric acid-A receptors (GABAARs) that rapidly internalize during status epilepticus (SE ...
Timothy B. C. Johnstone, Hilary S. McCarren, Jay Spampanato, F. Edward Dudek, John H. McDonough, Derk Hogenkamp, Kelvin W. Gee   +6 more
doaj   +1 more source

Antidotal and Neuroprotective Efficacies of a Prophylactic Patch against Sarin and Soman Poisonings in Guinea Pigs [PDF]

, 2021
Young‐Jo Song
openalex   +1 more source

Use of Hupresin To Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure

Analytical Chemistry, 2017
Toxicity from acute exposure to nerve agents and organophosphorus toxicants is due to irreversible inhibition of acetylcholinesterase (AChE) in the nervous system. AChE in red blood cells is a surrogate for AChE in the nervous system.
Seda Onder, L. Schopfer, J. Cashman, Ozden Tacal, Rudolph C. Johnson, T. Blake, O. Lockridge   +6 more
semanticscholar   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Colloidal stability of phytosynthesised gold nanoparticles and their catalytic effects for nerve agent degradation

Scientific Reports, 2021
Herein, Tilia sp. bract leachate was used as the reducing agent for Au nanoparticles (Au NPs) phytosynthesis. The colloidal properties of the prepared Au NPs were determined to confirm their stability over time, and the NPs were then used as active ...
Veronika Holišová, Martin Urban, Zuzana Konvičková, Marek Kolenčík, Pavel Mančík, Jiří Slabotinský, Gabriela Kratošová, Daniela Plachá   +7 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Optimization of Methods for Derivatization of Sarin, Soman, and VX Hydrolysis Products in the Process of Analyzing These Compounds Using Gas Chromatography [PDF]

Biuletyn Wojskowej Akademii Technicznej
The identification and quantification of degradation products of organophosphorus chemical warfare agents (OP-CWAs)are critical for retrospective and forensic analysis or evidence proceedings.
Hubert Suska, Stanisław Popiel
doaj   +1 more source

COF-supported zirconium oxyhydroxide as a versatile heterogeneous catalyst for Knoevenagel condensation and nerve agent hydrolysis

iScience, 2023
Summary: A composite of catalytic Lewis acidic zirconium oxyhydroxides (8 wt %) and a covalent organic framework (COF) was synthesized. X-ray diffraction and infrared (IR) spectroscopy reveal that COF’s structure is preserved after loading with zirconium
Pragalbh Shekhar, Venkata Swaroopa Datta Devulapalli, Reshma Reji, Himan Dev Singh, Aleena Jose, Piyush Singh, Arun Torris, Chatakudath P. Vinod, John A. Tokarz, III, John J. Mahle, Gregory W. Peterson, Eric Borguet, Ramanathan Vaidhyanathan   +12 more
doaj   +1 more source

Experimental and computational study of the inclusion complexes of β-cyclodextrin with the chemical warfare agent soman (GD) and commonly used simulants

, 2017
The hydrophobically driven inclusion complexation of the Chemical Warfare Agent (CWA) pinacolyl methylphosphonofluoridate (soman, or GD) by β-cyclodextrin (β-CD) is studied both experimentally and computationally.
M. Sambrook, Jack C. Vincent, Jayne A. Ede, I. Gass, P. Cragg   +4 more
semanticscholar   +1 more source