Results 81 to 90 of about 70,210 (257)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Relationships among clinical mastitis test-day records, somatic cell counts, and linear udder conformation traits in Czech dairy cows

Czech Journal of Animal Science
This study evaluated test-day records of clinical mastitis (CM), somatic cell count, and nine udder conformation traits. Somatic cell count was log-transformed into somatic cell score (SCS) in 10 periods, each 30 days long and overall, for the first ...
Jan Vařeka, Ludmila Zavadilová, Matúš Gašparík, Miloslava Štípková, Luboš Vostrý   +4 more
doaj   +1 more source

Correlations among somatic cell count, hygienic safety and quality of milk of primiparous cows [PDF]

Macedonian Veterinary Review, 2009
In this work we examined a total of 518 milk samples on the following parameters: somatic cell count (SCC), total bacteria count (CFU and IBC), fat, protein, lactose and dry matter non fat (DMNF) contents, which were obtained from primiparous cows ...
Adamov Nikola, Petkov Vladimir, Atanasov Branko   +2 more
doaj  

Buffalo milk: proteins electrophoretic profile and somatic cell count

Italian Journal of Animal Science, 2011
Water buffalo milk differs from the cow’s milk for greater fat and protein content, very important features in cheese making. Proteins, casein and whey-proteins in particular, are the most important factors determining cheese yield.
S. Mattii, B. Tommei, M. Pasquini
doaj   +1 more source

Cytospin Centrifuge in Differential Counts of Milk Somatic Cells

Journal of Dairy Science, 1982
A procedure was developed for a cytospin centrifuge to concentrate cells from milk onto microscope slides in a circle with 6 mm diameter. Differential somatic cell counts with cytospin were compared to the conventional hand smearing technique to ascertain variation in differential counts.
A M, Dulin, M J, Paape, B T, Weinland
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Epidemiologic Considerations in Reporting Herd Somatic Cell Counts

Journal of Dairy Science, 1986
The reporting of herd summaries of individual cow somatic cell counts differs between the nine Dairy Records Processing Centers. The objectives of this paper are to review the present reporting; to compare the methods used to calculate herd somatic cell counts; and to discuss the epidemiologic implications of these methods.
W D, Hueston, L E, Heider
openaire   +2 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

A study on impact of somatic cell count on physicochemical properties of pooled milk [PDF]

Journal of Veterinary and Animal Sciences, 2017
One hundred pooled milk samples were collected from organized farms and milk cooperatives in Thrissur district. All the samples were analyzed for somatic cell count, pH, titratable acidity, chloride and electrical conductivity.
J. P. Anu, C. T. Sathian, R. Geetha, K. Radha, K. Raji, V.L. Gleeja   +5 more
doaj