Results 351 to 360 of about 365,020 (403)

Somatic Cell Nuclear Transfer in Horses

Reproduction in Domestic Animals, 2008
ContentsThe cloning of equids was achieved in 2003, several years after the birth of Dolly the sheep and also after the cloning of numerous other laboratory and farm animal species. The delay was because of the limited development in the horse of more classical‐assisted reproductive techniques required for successful cloning, such as oocyte maturation ...
Silvia Colleoni, Giovanna Lazzari, Cesare Galli, Irina Lagutina, Roberto Duchi   +4 more
openaire   +2 more sources

Somatic cell nuclear transfer and centrosome inheritance

Hereditas (Beijing), 2008
The developmental competence of embryos cloned from somatic cells depends on the cellular event and molecular process, such as separation of chromosomes and reorganization of spindle after nuclear transfer. Centrosome, the main microtubule organizing centers in a cell, is crucial for reorganization of spindle and normal separation of chromosomes during
Hua-Bin Zhu, Wei-Hua Du, Dong Wang, Hai-Sheng Hao   +3 more
openaire   +3 more sources

Somatic Cell Nuclear Transfer in the Mouse

2008
Somatic cell nuclear transfer (SCNT) has become a unique and powerful tool for epigenetic reprogramming research and gene manipulation in animals since "Dolly," the first animal cloned from an adult cell was reported in 1997. Although the success rates of somatic cloning have been inefficient and the mechanism of reprogramming is still largely unknown,
Satoshi Kishigami, Teruhiko Wakayama
openaire   +3 more sources

Effects of Resveratrol on In Vitro Maturation of Porcine Oocytes and Subsequent Early Embryonic Development following Somatic Cell Nuclear Transfer.

Reproduction in domestic animals = Zuchthygiene, 2019
As a natural plant-derived antitoxin, resveratrol possesses several pharmacological activities. This study aimed to evaluate the effects of resveratrol addition on nuclear maturation, oocyte quality during in vitro maturation (IVM) of porcine oocytes ...
Xuefang Wang, Xiang-xing Zhu, Xingwei Liang, Hui-Yan Xu, Y. Liao, K. Lu, Sheng-sheng Lu   +6 more
semanticscholar   +1 more source

Somatic cell nuclear transfer

Australian Journal of Experimental Agriculture, 2004
Nuclear transfer research became front-page news when the birth of Dolly, the cloned ewe, was reported by Ian Wilmut and Keith Campbell in 1997. Since Dolly’s birth, offspring from many other species have been produced using somatic cell nuclear transfer.
openaire   +3 more sources

Bovine Somatic Cell Nuclear Transfer

2010
Somatic cell nuclear transfer (SCNT) is a technique by which the nucleus of a differentiated cell is introduced into an oocyte from which its genetic material has been removed by a process called enucleation. In mammals, the reconstructed embryo is artificially induced to initiate embryonic development (activation).
Pablo J. Ross, Jose B. Cibelli
openaire   +3 more sources

Epigenetic Reprogramming and Somatic Cell Nuclear Transfer

2023
Epigenetics is an area of genetics that studies the heritable modifications in gene expression and phenotype that are not controlled by the primary sequence of DNA. The main epigenetic mechanisms are DNA methylation, post-translational covalent modifications in histone tails, and non-coding RNAs. During mammalian development, there are two global waves
Luna N, Vargas, Márcia M, Silveira, Maurício M, Franco   +2 more
openaire   +2 more sources

Cloning of Monkeys by Somatic Cell Nuclear Transfer

2020
Somatic cell nuclear transfer (SCNT) is a promising method to establish genetically modified monkeys with identical genetic background as models in biomedical research. We have recently cloned monkeys by optimization of the SCNT protocols and inclusion of the epigenetic modulator.
Zhen Liu, Shiyu Sun, Zhaodi Liao, Qiang Sun   +3 more
openaire   +3 more sources

Human somatic cell nuclear transfer and cloning

Fertility and Sterility, 2012
This document presents arguments that conclude that it is unethical to use somatic cell nuclear transfer (SCNT) for infertility treatment due to concerns about safety; the unknown impact of SCNT on children, families, and society; and the availability of other ethically acceptable means of assisted reproduction.
Judith Daar, Leslie Francis, Sean Tipton, Paula Amato, Robert W. Rebar, Mark Gibson, John A. Robertson, Jean Benward, Bonnie Steinbock, Richard H. Reindollar, Mark Sauer, Steven Ralston, Monique Spillman, Robert Brzyski, Andrea Stein, Andrea Mechanick Braverman, Senait Fisseha, Dolores J. Lamb, Bruce Wilder   +18 more
openaire   +3 more sources

Cattle Cloning by Somatic Cell Nuclear Transfer

2023
Cloning by somatic cell Nuclear Transfer (SCNT) is a powerful technology capable of reprograming terminally differentiated cells to totipotency for generating whole animals or pluripotent stem cells for use in cell therapy, drug screening, and other biotechnological applications. However, the broad usage of SCNT remains limited due to its high cost and
Juliano Rodrigues, Sangalli, Rafael Vilar, Sampaio, Tiago Henrique Camara, De Bem, Lawrence Charles, Smith, Flávio Vieira, Meirelles   +4 more
openaire   +2 more sources