Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
FACTORS AFFECTING THE VISCOMETRIC METHOD FOR ESTIMATING THE SOMATIC CELL COUNT OF COW'S MILK [PDF]
L. R. Fell+2 more
openalex +1 more source
Construction and mechanism analysis of the sex reversal model of chicken gonadal somatic cells. [PDF]
Lv X+8 more
europepmc +1 more source
MND1 enables homologous recombination in somatic cells primarily outside the context of replication. [PDF]
Koob L+11 more
europepmc +1 more source
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan+4 more
wiley +1 more source
Proteomic analysis of Buffalo milk somatic cells reveals metabolomic and immunological transitions during early lactation. [PDF]
Kittur PM+7 more
europepmc +1 more source
A Study on Differential Biomarkers in the Milk of Holstein Cows with Different Somatic Cells Count Levels. [PDF]
She Y+10 more
europepmc +1 more source
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Human Antigen and Enzyme Markers in Man-Chinese Hamster Somatic Cell Hybrids: Evidence for Synteny Between the HL-A, PGM 3 , ME 1 , and IPO-B Loci [PDF]
H. van Someren+5 more
openalex +1 more source
Prolonged persistence of mutagenic DNA lesions in somatic cells. [PDF]
Spencer Chapman M+25 more
europepmc +1 more source