Results 221 to 230 of about 608,220 (356)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Single-Cell Analysis of Host Responses in Bovine Milk Somatic Cells (bMSCs) Following HPAIV Bovine H5N1 Influenza Exposure. [PDF]

Viruses
Singh G, Kafle S, Assato P, Goraya M, Morozov I, Richt JA.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

A Non–Cell Autonomous Role of E ( z ) to Prevent Germ Cells from Turning on a Somatic Cell Marker

, 2014
Suk Ho Eun, Zhen Shi, Kairong Cui, Keji Zhao, Xin Chen   +4 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Fate erasure logic of gene networks underlying direct neuronal conversion of somatic cells by microRNAs. [PDF]

Cell Rep
Cates K, Yuan L, Yang Y, Yoo AS.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells. [PDF]

J Biol Chem
Ishida-Ishihara S, Yaguchi K, Miura S, Nomura R, Wang Q, Yoshizawa K, Sato K, Yang G, Veszelyi K, Banhegyi G, Margittai E, Uehara R.   +11 more
europepmc   +1 more source

Antibiotic therapy for subclinical mastitis in early lactation : effects on infection, somatic cell counts and milk production : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University

, 1982
Samson Mwakasagule Mwakipesile
openalex   +1 more source