Reduced treatment-emergent sexual dysfunction as a potential target in the development of new antidepressants [PDF]
Pleasurable sexual activity is an essential component of many human relationships, providing a sense of physical, psychological, and social well-being.
Masdrakis, V.G. +2 more
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A Case for Somatic Practices as Embodied Mindfulness
Presenting convergences between mindfulness and somatic practices, this article makes a case for somatic practices as embodied mindfulness. It discusses historical origins as well as brief comments supporting some shared value systems and qualities ...
Weber, Becca
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Somatic instability of the expanded GAA triplet-repeat sequence in Friedreich ataxia progresses throughout life [PDF]
Friedreich ataxia (FRDA) patients are homozygous for expanded GAA triplet-repeat alleles in the FXN gene. Primary neurodegeneration involving the dorsal root ganglia (DRG) results in progressive ataxia.
Ramussen, A +29 more
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Generation of somatic mitochondrial DNA-replaced cells for mitochondrial dysfunction treatment
Mitochondrial diseases currently have no cure regardless of whether the cause is a nuclear or mitochondrial genome mutation. Mitochondrial dysfunction notably affects a wide range of disorders in aged individuals, including neurodegenerative diseases ...
Hideki Maeda +4 more
doaj +1 more source
Chest pain and the role of somatic dysfunction [PDF]
Abstract The symptom of chest pain may be a result or manifestation of somatic dysfunction of the musculoskeletal system. Chest pain is a common chief complaint among patients in a family practice office or in the emergency room. Various intrathoracic and extra thoracic factors may be responsible.
C M, Wax, D S, Abend, P H, Pearson
openaire +2 more sources
Wen-Juan Gao,1,* Wen-Juan Bao,2,* Su-Juan Sun3 1Neurology, Hebei General Hospital, Shijiazhuang City, Hebei 050051, People’s Republic of China; 2Department of Hepato-Biliary-Pancreatic Surgery, Hebei General Hospital, Shijiazhuang City, Hebei ...
Gao WJ, Bao WJ, Sun SJ
doaj
Human psychophysiological responses to visceral and somatic pain – the development of integrated, reproducible human pain phenotypes [PDF]
PhDBackground Pain is the ubiquitous human experience, yet displays considerable inter- and intraindividual variability in health and disease. Many factors have been proposed to account for these differences.
Farmer, Adam Donald
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Effectiveness of Mulligan’s Sustained Natural Apophyseal Glide (SNAG) over First Rib in Reducing Pain and Improving Cervical Rotation in Individuals with Mechanical Neck Dysfunction [PDF]
Introduction: Mechanical Neck Pain (MNP) is any type of pain caused by placing abnormal stress and strain on the structures that constitute the vertebral column. Elevated first rib dysfunction is one potential somatic lesion that could lead to neck pain.
Bhattarai Prayerna +3 more
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The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus [PDF]
In systemic lupus erythematosus (SLE) it has been hypothesized that self-reactive B cells arise from virgin B cells that express low-affinity, nonpathogenic germline V genes that are cross-reactive for self and microbial antigens, which convert to high ...
Stott, DI +11 more
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Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?
A great deal of evidence supports a role for mitochondrial dysfunction in the pathogenesis of Parkinson's disease (PD), although the origin of the mitochondrial dysfunction in PD remains unclear.
Joanne Clark, Ying Dai, David K. Simon
doaj +1 more source

