Results 171 to 180 of about 199,006 (315)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Regulatory non-coding somatic mutations as drivers of neuroblastoma. [PDF]

Br J Cancer
Montella A, Tirelli M, Lasorsa VA, Aievola V, Cerbone V, Manganiello R, Iolascon A, Capasso M.   +7 more
europepmc   +1 more source

Role of somatic mutations in the evolution of higher plants [PDF]

, 1997
Francesco D’Amato
openalex   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

The role of recurrent somatic mutations that alter conserved m⁶A motifs in human cancer. [PDF]

NAR Cancer
Artz O, White JR, Rousseau B, Argiles G, Foote MB, Johannet P, Patel M, Abdelfattah S, Patel S, Wilde C, Mieles D, Diaz LA.   +11 more
europepmc   +1 more source

Cytological detection of somatic mutations in Tradescantia induced by ethanol.

, 1986
Rafael Villalobos‐Pietrini, R. Hernandez, Ma. de los Angeles Guadarrama, Sandra Gómez‐Arroyo   +3 more
openalex   +2 more sources

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

Somatic mutations in Brazilian patients with paroxysmal nocturnal hemoglobinuria: a comprehensive analysis. [PDF]

Front Med (Lausanne)
Eiko Yamakawa P, Perez Gomes C, Ribeiro Mendes A, Cesar Justino de Oliveira C, Porto Freitas F, Bettoni F, Xavier Dos Santos E, Campos de Molla V, Vescovi Gonçalves M, Branquinho J, Ribeiro Nogueira B, Bosco Pesquero J, Arrais-Rodrigues C.   +12 more
europepmc   +1 more source

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects [PDF]

, 1997
Pierre Hainaut, Thierry Soussi, Benny Shomer, Monica Hollstein, Marc S. Greenblatt, Eivind Hovig, C C Harris, Ruggero Montesano   +7 more
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source