Results 171 to 180 of about 1,061,050 (301)

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Diversity at the HYP1 locus in potato cyst nematodes does not result from developmentally-programmed somatic mutations. [PDF]

PLoS One
Hanlon VCT, Sonawala U, Raza CAA, Kalkert L, Harpum G, Burkhardt LA, Helder J, Eves-van den Akker S.   +7 more
europepmc   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Somatic mutations reveal hyperactive Notch signaling in prurigo nodularis. [PDF]

JCI Insight
Rajeh A, Shahsavari S, Cornman H, Kollhoff A, Gupta A, Szeto MD, Kambala A, Oladipo OO, Parthasarathy V, Deng J, Marani M, Shahsavari S, Yossef SM, Vaddaraju V, Adawi W, Akiska YM, Gage DM, Wheelan S, Pritchard T, Kwatra MM, Semenov YR, Gusev A, Ho WJ, Yegnasubramanian S, Kwatra SG.   +24 more
europepmc   +1 more source

Extrusion‐Based Bioprinting of Living Bioinks for Tissue and Organ Engineering

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting is presented as the most versatile route for fabricating living, heterogeneous tissues. Its ability to combine diverse bioinks, support matrices, and advanced printhead geometries transforms familiar constraints into powerful biofabrication opportunities.
Eric Silberman, Ester Sapir Baruch, Roni Cohen, Assaf Shapira, Tal Dvir   +4 more
wiley   +1 more source

Integrative benchmarking and automation of clonal reconstruction of somatic mutations in single-sample tumor genome analysis. [PDF]

BMC Bioinformatics
Masliakova M, Lefever S, Vandesompele J.
europepmc   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

Somatic mutations and clonal evolution in normal tissues and cancer development. [PDF]

Exp Mol Med
Yoshida K.
europepmc   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Sensitive detection of somatic mutations in GC-rich cancer gene promoters. [PDF]

NAR Cancer
Qi M, Dave PS, Francis N, DeFelice M, Pollock S, Corbitt H, Mitsiades IR, Wang G, Frere P, Fox A, Khitrov G, Petersen C, Larkin K, Hamilton S, Ellisen LW, Gulhan DC, Hidalgo-Miranda A, Lennon N, Cibulskis C, Rheinbay E.   +19 more
europepmc   +1 more source