Results 321 to 330 of about 1,861,621 (385)

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Identifying somatic driver mutations in cancer with a language model of the human genome

Guangjian Zeng, Chengzhi Zhao, Guanpeng Li, Zhengyang Huang, Jinhu Zhuang, Xiaohua Liang, Xiaxia Yu, Shenying Fang   +7 more
openalex   +1 more source

Somatic mutations and the efficacy of immunosuppressive therapy in severe/very severe aplastic anemia and transfusion-dependent nonsevere aplastic anemia. [PDF]

Ann Hematol
Ye L, Zhang L, Zhang D, Zhao X, Li Y, Xiong Y, Fang L, Ge M, Shi J, Zhang F, Jing L.   +10 more
europepmc   +1 more source

Somatic mutations in Brazilian patients with paroxysmal nocturnal hemoglobinuria: a comprehensive analysis. [PDF]

Front Med (Lausanne)
Eiko Yamakawa P, Perez Gomes C, Ribeiro Mendes A, Cesar Justino de Oliveira C, Porto Freitas F, Bettoni F, Xavier Dos Santos E, Campos de Molla V, Vescovi Gonçalves M, Branquinho J, Ribeiro Nogueira B, Bosco Pesquero J, Arrais-Rodrigues C.   +12 more
europepmc   +1 more source

The role of recurrent somatic mutations that alter conserved m⁶A motifs in human cancer. [PDF]

NAR Cancer
Artz O, White JR, Rousseau B, Argiles G, Foote MB, Johannet P, Patel M, Abdelfattah S, Patel S, Wilde C, Mieles D, Diaz LA.   +11 more
europepmc   +1 more source

Toward the Systemic Replacement of Mitochondrial DNA with Somatic Mutations

Michael Renteln
openalex   +2 more sources

Prognostic impact of somatic mutations and additional chromosomal abnormalities in patients with myelodysplastic syndromes and chromosome 20q deletion. [PDF]

Clin Exp Med
Huang X, Li X, Liu Q, Guo J, Chen J, Zhou L, Song L, Zhang Z, Su J, Zhang Y, Yan M, He Q, Wu D, Xu F, Chang C, Wu L.   +15 more
europepmc   +1 more source

Contribution of germline and somatic mutations to risk of neuromyelitis optica spectrum disorder. [PDF]

Cell Genom
Yata T, Sato G, Ogawa K, Naito T, Sonehara K, Saiki R, Edahiro R, Namba S, Watanabe M, Shirai Y, Yamamoto K, NamKoong H, Nakanishi T, Yamamoto Y, Hosokawa A, Yamamoto M, Japan MS/NMOSD biobank, BioBank Japan Project, Japan COVID-19 Task Force, Oguro-Igashira E, Nii T, Maeda Y, Nakajima K, Nishikawa R, Tanaka H, Nakayamada S, Matsuda K, Nishigori C, Sano S, Kinoshita M, Koike R, Kimura A, Imoto S, Miyano S, Fukunaga K, Mihara M, Shimizu Y, Kawachi I, Miyamoto K, Tanaka Y, Kumanogoh A, Niino M, Nakatsuji Y, Ogawa S, Matsushita T, Kira JI, Mochizuki H, Isobe N, Okuno T, Okada Y.   +49 more
europepmc   +1 more source

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Somatic Mutations in “Benign” Disease

New England Journal of Medicine, 2021
Somatic Mutations in “Benign” Disease DNA mutations occur in nearly every tissue throughout the human life span and accumulate at various rates in different tissues according to intrinsic and extri...
Osama, Dasa, Thomas A, Pearson
semanticscholar   +6 more sources