Results 61 to 70 of about 590,094 (251)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Somatic Symptom Disorders and Factitious Disorders

, 2017
In this chapter topics on somatoform disorders will be reviewed including conversion disorder and hypochondriasis/somatic symptom ...
Harvinder Singh, Juan Young, Isabella Michna   +2 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Time-dynamic associations between symptom-related expectations, self-management experiences and somatic symptom severity in everyday life: an ecological momentary assessment study with university students

BMJ Open
Objective The present study investigated the associations between symptom-related expectations, self-management experiences and expectation framing on somatic symptom severity in university students in two conditions (positive or standard expectation ...
Bernd Löwe, Yvonne Nestoriuc, Anne Toussaint, Stefanie Hahn, Franz Pauls, Simon Kirchhof   +5 more
doaj   +1 more source

Two Myths About Somatic Markers [PDF]

, 2012
Research on patients with damage to ventromedial frontal cortices suggests a key role for emotions in practical decision making. This field of investigation is often associated with Antonio Damasio’s Somatic Marker Hypothesis–a putative account of the ...
Linquist, Stefan, Bartol, Jordan
core  

A multi-level decomposition of variance in somatic symptom reporting in families with adolescent children

, 2006
OBJECTIVES: This paper examines four different levels of possible variation in symptom reporting: occasion, day, person and family. DESIGN: In order to rule out effects of retrospection, concurrent symptom reporting was assessed prospectively using a ...
Michel, Gisela
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Symptom network analysis of depressive and somatic symptoms and suicide risk indicators in treatment-naïve adolescents with first-episode depression

BMC Psychiatry
Background Depression in adolescents often co-occurs with suicidal ideation and behaviors. In clinical practice, many adolescents with depression report prominent somatic complaints, yet the relevance of these somatic symptoms to different forms of ...
Guixia Liu, Xinning An, Xuebin Wen, Hong Luo, Xinglian Wang, Hao Ren, Xiufen Zhong, Yue Gao, Shixin Yu, Jin Zhang, Ghalia Zainab Jafri, Haitang Qiu   +11 more
doaj   +1 more source

The dimensionality and somatisation correlates of ICD-11 prolonged grief disorder

European Journal of Psychotraumatology
Background: Somatisation is common among individuals experiencing prolonged grief, yet the specificity of associations between International Classification of Diseases (ICD-11) Prolonged Grief Disorder (PGD) symptom dimensions and somatic distress ...
Pearse McCusker, Clare Killikelly, Mary-Frances O'Connor, Orla McBride, James Cunningham, Jamie Murphy, Michael Duffy, Mark Shevlin   +7 more
doaj   +1 more source