Results 181 to 190 of about 49,786 (271)

Somatic Symptom Disorder Is Associated with Cough Hypersensitivity and Poor Response to Anti-Reflux Therapy in Patients with Gastroesophageal Reflux-Induced Chronic Cough. [PDF]

J Clin Med
Zhou Y, Zhang T, In J, Wang S, Yuan J, Sha B, Bai H, Wu H, Yu L, Xu X.   +9 more
europepmc   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

Cyberchondria, Health Anxiety, and Sleep Quality: An Observational Cross-Sectional Study of Adults with and Without Psychosomatic Disorders. [PDF]

Healthcare (Basel)
Elashram REM, Bashshar AMAA, Abo-Bakr ASS, Al-Ghamdi AM.   +3 more
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Disability, distress and delayed access to care in functional neurological disorder: cross-sectional study from an Australian tertiary clinic. [PDF]

BJPsych Open
Moss RSL, Lennon MJ, Anne S, Swift E, Lo JW, Walpola IC, Connors MH, Sachdev PS, Mohan A.   +8 more
europepmc   +1 more source

Gastrointestinal motility disorders in children: ontogenesis, patophysiology, epidemiology, clinical features and management

, 2008
Boccia, Gabriella
core  

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Overview of somatization through three historical lenses and future directions. [PDF]

Discov Ment Health
Garde V, Churchill M, Greenslade J, Watt K, Mallett AJ.   +4 more
europepmc   +1 more source

Suicidality in Somatic Symptom and Related Disorders : A Systematic Review [PDF]

, 2021
Torres, Michael, Löwe, Bernd, Schmitz, Samantha, Pienta, John, Van Der Feltz-Cornelis, Christina Maria, Fiedorowicz, Jess   +5 more
openaire   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source