Results 51 to 60 of about 48,505 (276)

Facing somatic symptom disorder in the emergency department

, 2019
Somatic symptom disorder is a condition in which a patient's subjective report of physical symptoms is associated with distress; disruption of day-to-day functioning; or disproportionate thoughts, feelings and behaviours regarding the symptoms, whether ...
Barbi, Egidio, Cozzi, Giorgio
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Associations between emotional awareness deficits and somatic symptoms in a community and clinical populations: a cross-sectional study

BMC Psychology
Background Deficits in emotional awareness may contribute to the development and maintenance of somatic symptoms. This study explored emotional awareness deficits and their association with somatic symptoms among individuals with a high somatic symptom ...
Sunyoung Kang, Chun Il Park, Se Joo Kim, Jee In Kang   +3 more
doaj   +1 more source

Findings Consistent with a Breast Implant–associated Somatic System Disorder (BIA-SSD) Among Patients Self-reporting Breast Implant Illness

Plastic and Reconstructive Surgery, Global Open
Background:. Self-reported breast implant illness (BII) has been found to be associated with anxiety as well as medically diagnosed anxiety and depression.
Stephen D. Bresnick, MD, Susie Morris, MD, Carlito Lagman, MD   +2 more
doaj   +1 more source

Selective serotonin reuptake inhibitors in the treatment of generalized anxiety disorder [PDF]

, 2002
Selective serotonin reuptake inhibitors have proven efficacy in the treatment of panic disorder, obsessive–compulsive disorder, post-traumatic stress disorder and social anxiety disorder.
Buis, C., Mayers, A.G., Baldwin, D.S.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Body drawings as an assessment tool for body-relatedness in patients with severe somatic symptom disorder

, 2015
Background: A core feature of somatic symptom disorder is the troubled relation of patients to their body. Efforts to assess body-relatedness have been focusing on self-report questionnaires, which may overlook important aspects of body-relatedness ...
van Broeckhuysen-Kloth, S., Kalisvaart, H., Buhring, M., van Busschbach , J., Geenen, R.   +4 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Many faces of somatic symptom disorders [PDF]

International Review of Psychiatry, 2013
Somatic symptom disorders are disorders with prominent somatic or bodily symptoms. They are common in healthcare settings and with varied features.
openaire   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source