Results 71 to 80 of about 27,641 (183)

Leveraging genetic propensity to identify modifiable factors for the age at onset of Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Knowledge of modifiable factors influencing age at onset (AAO) of Alzheimer's disease (AD) remains limited. This study utilizes genetic information to uncover such factors. METHODS Using 43 exposure genome‐wide association studies (GWAS) summary statistics, we calculated corresponding polygenic scores (PGS) for 9219 AD cases and ...
Yi‐Ju Li, Jong Ok La, Adam Naj, Eden R. Martin   +3 more
wiley   +1 more source

Modern approaches to psychoterapy of somatoform disorders

Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
The scientific review focuses on the relevant for modern medicine problem of psychotherapy of somatoform disorders (SFD). It is based on the analysis of 106 publications on this topic (46 of them in Russian and 60 in English). The search for publications
A. I. Mukhametova, V. V. Vasilyev
doaj   +3 more sources

Viewing an alpine environment positively affects emotional analytics in patients with somatoform, depressive and anxiety disorders as well as in healthy controls

BMC Psychiatry, 2020
Background Patients with somatoform, depressive or anxiety disorders often don’t respond well to medical treatment and experience many side effects. It is thus of clinical relevance to identify alternative, scientifically based, treatments.
Katharina Hüfner, Cornelia Ower, Georg Kemmler, Theresa Vill, Caroline Martini, Andrea Schmitt, Barbara Sperner-Unterweger   +6 more
doaj   +1 more source

Validity and responsiveness of the EQ-5D in assessing and valuing health status in patients with somatoform disorders [PDF]

, 2013
Background: The EQ-5D is a generic questionnaire providing a preference-based index score applicable to cost-utility analysis. This is the first study to validate the EQ-5D in patients with somatoform disorders.
Brettschneider, Christian, Herzog, Wolfgang, Kaufmann, Claudia, Konnopka, Alexander, König, Hans-Helmut, Schäfert, Rainer   +5 more
core   +1 more source

Combination of Serum Neurofilament Light Chain and Serum Cardiac Troponin T as Biomarkers Improves Diagnostic Accuracy in Amyotrophic Lateral Sclerosis

Annals of Neurology, Volume 99, Issue 2, Page 408-417, February 2026.
Objective We aimed to evaluate the clinical utility of serum neurofilament light chain (sNfL) and cardiac troponin T (cTnT) in amyotrophic lateral sclerosis (ALS) and assess whether their combination improves diagnostic accuracy. Methods We retrospectively analyzed 293 ALS patients, 85 neurodegenerative disease controls, and 29 healthy controls.
Paula Lindenborn, Rachel Fabian, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Sarah Bernsen, Patrick Weydt   +6 more
wiley   +1 more source

Quality of life prognosis in patients with somatoform disorders with sleep disorders

Medičnì Perspektivi
In recent years, the impact of psychotraumatic factors has been increasing, leading to an increased prevalence of psychogenic disorders. Patients with somatoform disorders place a significant burden on the healthcare system.
V.V. Ogorenko, I.I. Makarova, A.V. Shornikov   +2 more
doaj   +1 more source

Effective group training for patients with unexplained physical symptoms: A randomized controlled trial with a non-randomized one-year follow-up [PDF]

, 2012
Background: Although cognitive-behavioral therapy for Unexplained Physical Symptoms (UPS) is effective in secondary care, studies done in primary care produced implementation ...
Busschbach, J.J. (Jan) van, Kooiman, C.G. (Cornelis), Rood, Y.R. (Yanda) van, Spijker, A. (Adriaan) van 't, Timman, R. (Reinier), Zonneveld, L.N.L. (Lyonne)   +5 more
core   +5 more sources

Neurostructural Substrates of Hierarchical Dimensions of Internalizing Symptoms in Youth

Human Brain Mapping, Volume 47, Issue 2, February 1, 2026.
Using data from over 11,000 9‐ to 10‐year olds in the ABCD Study, we examined the hierarchical structure of internalizing symptoms and their neurostructural correlates. We found that general internalizing, distress, and cognitive symptoms were associated with widespread reductions in gray matter volume and surface area, while fear symptoms showed more ...
E. Leighton Durham, Tyler M. Moore, Kaitlynn E. Ellis, Shuti Wang, Hee Jung Jeong, Gabrielle E. Reimann, Camille Archer, Antonia N. Kaczkurkin   +7 more
wiley   +1 more source

A systematic review of brain health in adults with chronic pain

Anaesthesia, Volume 81, Issue 2, Page 248-262, February 2026.
Summary Introduction Recent research has linked chronic pain with an increased risk of clinical dementia diagnosis. Yet structural and functional brain changes associated with chronic pain and their potential role in accelerating brain ageing have not been characterised comprehensively.
Angeline Lee, Sara Al‐Dahwi, Thomas Angell, Abinaya Arulalagan, Ryan Bloxsom, Harry Clarkson, Rose Faure, Soutiam Goodarzi, Minshu Gupta, Adithya Kale, Kin Lam, Freyia Mahon‐Daly, Chloe Parry, Vidushi Pradhan, Finlay Ryan‐Phillips, Suraj Shah, Serina Sidhu, John Smiddy, Aparna Sridhar, Syed F. Tahmid, Robert Wight, Nia Roberts, Anya Topiwala   +22 more
wiley   +1 more source

Emotional disorders: Cluster 4 of the proposed meta-structure for DSM-V and ICD-11 [PDF]

, 2009
Background The extant major psychiatric classifications DSM-IV, and ICD-10, are atheoretical and largely descriptive. Although this achieves good reliability, the validity of a medical diagnosis would be greatly enhanced by an understanding of risk ...
Andrews, G., Goldberg, D. P, Hobbs, M. J, Krueger, R. F   +3 more
core   +2 more sources