Results 31 to 40 of about 7,343 (202)

Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury

open access: yeseLife, 2018
Neuropathic pain resulting from nerve injury can become persistent and difficult to treat but the molecular signaling responsible for its development remains poorly described.
Josette J Wlaschin   +6 more
doaj   +1 more source

Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons

open access: yeseLife, 2018
Piezo2 ion channels are critical determinants of the sense of light touch in vertebrates. Yet, their regulation is only incompletely understood. We recently identified myotubularin related protein-2 (Mtmr2), a phosphoinositide (PI) phosphatase, in the ...
Pratibha Narayanan   +7 more
doaj   +1 more source

More than skin deep: body representation beyond primary somatosensory cortex [PDF]

open access: yes, 2010
The neural circuits underlying initial sensory processing of somatic information are relatively well understood. In contrast, the processes that go beyond primary somatosensation to create more abstract representations related to the body are less clear.
Azanon, E.   +2 more
core   +1 more source

Human Stem Cell-Derived TRPV1-Positive Sensory Neurons: A New Tool to Study Mechanisms of Sensitization

open access: yesCells, 2022
Somatosensation, the detection and transduction of external and internal stimuli such as temperature or mechanical force, is vital to sustaining our bodily integrity.
Katrin Schrenk-Siemens   +8 more
doaj   +1 more source

A 2.5-D representation of the human hand [PDF]

open access: yes, 2012
Primary somatosensory maps in the brain represent the body as a discontinuous, fragmented set of 2-D skin regions. We nevertheless experience our body as a coherent 3-D volumetric object.
Haggard, P., Longo, Matthew R.
core   +1 more source

Decoupling kinematics and mechanics reveals coding properties of trigeminal ganglion neurons in the rat vibrissal system

open access: yeseLife, 2016
Tactile information available to the rat vibrissal system begins as external forces that cause whisker deformations, which in turn excite mechanoreceptors in the follicle.
Nicholas E Bush   +6 more
doaj   +1 more source

Somatosensation and the First Person

open access: yesReview of Philosophy and Psychology, 2022
AbstractExperientialism about the sense of bodily ownership is the view that there is something it is like to feel a body as one’s own. In this paper I argue for a particular experientialist thesis. I first present a puzzle about the relation between bodily awareness and self-consciousness, and introduce a somewhat underappreciated view on the sense of
openaire   +2 more sources

Somatosensation assessment using the NIH Toolbox [PDF]

open access: yesNeurology, 2013
Touch sensation is one element of sensory function. As such, somatosensation is one of the sensory domains included in the NIH Toolbox, which is an assessment battery for measuring a range of human functions including emotional health, sensation, cognition, and motor function.
Dunn, Winnie.   +7 more
openaire   +2 more sources

Beyond somatosensation: Mrgprs in mucosal tissues

open access: yesNeuroscience Letters, 2021
Mas-related G coupled receptors (Mrgprs) are a superfamily of receptors expressed in sensory neurons that are known to transmit somatic sensations from the skin to the central nervous system. Interestingly, Mrgprs have recently been implicated in sensory and motor functions of mucosal-associated neuronal circuits.
Juan M. Inclan-Rico   +2 more
openaire   +3 more sources

Vicarious experiences and detection accuracy while observing pain and touch: the effect of perspective taking [PDF]

open access: yes, 2015
In this study, we investigated the effects of observing pain and touch in others on vicarious somatosensory experiences and the detection of subtle somatosensory stimuli.
Crombez, Geert   +3 more
core   +2 more sources

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