Results 81 to 90 of about 36,401 (248)

Modulation of the Somatosensory Evoked Potential by Attention and Spinal Cord Stimulation. [PDF]

open access: yesFront Neurol, 2021
Niso G   +3 more
europepmc   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Association of perioperative intravenous lignocaine and intraoperative neuromonitoring in adolescent idiopathic scoliosis surgery: a retrospective study

open access: yesPerioperative Medicine
Background The use of intravenous (IV) lignocaine as an analgesic adjunct is increasing, but its impact on intraoperative neurophysiological monitoring (IONM) remains unclear.
Siti Nadzrah Yunus   +8 more
doaj   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi   +12 more
wiley   +1 more source

A De Novo ATP1A3 p.Arg995His Variant in a Patient With an Adult‐Onset Primary Lateral Sclerosis‐Like Syndrome

open access: yesClinical Genetics, EarlyView.
A 43‐year‐old woman developed a progressive adult‐onset upper motor neuron syndrome fulfilling the clinical criteria for primary lateral sclerosis (PLS), with mild cerebellar involvement. Genetic testing identified a de novo ATP1A3 p.Arg995His variant affecting a highly conserved residue within the transmembrane M8 domain.
Pablo Hernandez‐Vitorique   +4 more
wiley   +1 more source

Lower Olfactory Sensitivity in Retronasal Olfaction

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives To directly compare orthonasal and retronasal olfactory function using the recently introduced odorant containers, which enable retronasal stimulation without gustatory or somatosensory involvement. Design Experimental study employing a within‐subjects design. Setting Laboratory‐based olfactory testing facility.
Shalini Balaji Vilvanathan   +1 more
wiley   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa   +6 more
wiley   +1 more source

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