Results 211 to 220 of about 127,626 (314)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Chronic Co-administration of Methylphenidate and Fluoxetine Reduces Striatal NMDA Receptor Binding in Adolescent Rats. [PDF]

Neurochem Res
Lagamjis G, Slayton D, Lu H, Hoerner C, Lantry AM, Marion M, Elman D, Hadjiargyrou M, Komatsu D, Thanos PK.   +9 more
europepmc   +1 more source

Neuromorphological Alterations in the Somatosensory System of Adolescent Idiopathic Scoliosis: A Systematic Review of Magnetic Resonance Imaging Studies. [PDF]

Children (Basel)
Wu Q, Chen Z, Chen K, Li X, Guo H, Zhou X, Liang J, Du Q.   +7 more
europepmc   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

Developmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa, Kirsi Mikkonen, Marjo Metsäranta, Sanna Toiviainen‐Salo, Sampsa Vanhatalo, Leena Lauronen, Päivi Nevalainen   +6 more
wiley   +1 more source

Somatosensory Evoked Potentials in Spinocerebellar Ataxia Type 3 and Type 10. [PDF]

Cerebellum
Coutinho L, Fustes OJH, Camargo CHF, Stoliar GA, Germiniani FMB, Raskin S, Ashizawa T, Kay CSK, Lorenzoni PJ, Ducci RD, Scola RH, Teive HAG.   +11 more
europepmc   +1 more source

Multisensory and sensorimotor interactions in speech perception

Frontiers in Psychology, 2015
Kaisa eTiippana, Riikka eMöttönen, Jean-Luc eSchwartz   +2 more
doaj   +1 more source

Short-term sensorimotor practice reduces somatosensory temporal discrimination threshold and enhances somatosensory cortex excitability. [PDF]

Clin Neurophysiol Pract
Yoshida N, Suzuki T, Ogahara K, Kokue T, Higashi T, Sugawara K.   +5 more
europepmc   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

Precise tactile localization on tools in two dimensions. [PDF]

iScience
Longo MR, Forde R, Joel J, Miller LE, Farnè A.   +4 more
europepmc   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source