Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To characterise the pharmacokinetics (PKs) and safety of BM2216 sustained‐release (SR) tablets after single‐dose oral administration under fasted/fed conditions in healthy participants, assess the effect of food and dose proportionality, and compare the single and multiple‐dose PK of BM2216 SR tablets with mirogabalin besylate tablets to ...
Peiyang Song +6 more
wiley +1 more source
LR3-LI4 needling side and configuration are associated with phase-specific cortical activation and network organization: a functional near-infrared spectroscopy study in healthy adults. [PDF]
Front NeurolXie Y +5 more
europepmc +1 more source
The FEBS Journal, EarlyView.Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester +11 more
wiley +1 more source
Trigeminal nociceptive somatotopy across brainstem and cortex and their functional interactions. [PDF]
J Headache PainScutelnic A +4 more
europepmc +1 more source
Visual, vestibular, and ocular motor changes during nitroglycerin‐triggered vestibular migraine
Headache: The Journal of Head and Face Pain, EarlyView.Plain Language Summary Vestibular migraine (VM) is a common cause of intermittent dizziness, but there have been no studies with provoked (induced) VM used to characterize how the vestibular and ocular (vision) systems interact. We injected 20 patients with VM with nitroglycerin to provoke an attack and used a specialized camera to record their eye ...
Maria Dolores Villar‐Martinez +4 more
wiley +1 more source
Whole-Brain Monosynaptic Inputs to and Axonal Projections From Posterior Insular Cortex GABAergic Neurons in Mice. [PDF]
CNS Neurosci TherQi WQ +6 more
europepmc +1 more source
Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications
International Journal of Dermatology, EarlyView.Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta +4 more
wiley +1 more source
Editorial: New perspectives on the role of sensory feedback in speech production, volume III. [PDF]
Front Hum NeurosciJones JA, Houde JF.
europepmc +1 more source
Journal of Clinical Periodontology, EarlyView.ABSTRACT Objective To assess the impact of keratinized mucosa width (KMW) and mucosal thickness (MT) on peri‐implant conditions over 25 years in patients with adequate oral hygiene enrolled in regular supportive peri‐implant care. Methods Partially edentulous patients rehabilitated with tissue‐level implants were clinically and radiographically ...
Emilio Couso‐Queiruga +5 more
wiley +1 more source
Cognitive reappraisal modulates neural responses to aversive sensory stimulation in autistic youth
Journal of Child Psychology and Psychiatry, EarlyView.Background Sensory over‐responsivity (SOR) is highly prevalent and impairing in autism spectrum disorder (ASD). SOR has been associated with sensory‐limbic hyperresponsivity and reduced prefrontal top‐down regulation during sensory stimulation. There are few evidence‐based treatments for SOR, but cognitive reappraisal, an emotion regulation strategy ...
Urvi T. Shah +7 more
wiley +1 more source