Results 261 to 270 of about 645,997 (394)

Involvement of NMDA and Non-NMDA Receptors in the Neuronal Responses of the Primary Motor Cortex to Input from the Supplementary Motor Area and Somatosensory Cortex: Studies of Task-Performing Monkeys.

, 1998
Keisetsu Shima, Jun Tanji
openalex   +2 more sources

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

snRNA-seq atlas of the juvenile mouse primary whisker somatosensory cortex (wS1).

Salwan Butrus (11682926), Hannah R. Monday (21364325), Christopher J. Yoo (21364328), Daniel E. Feldman (21364331), Karthik Shekhar (3857107)   +4 more
openalex   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans

Nature Neuroscience, 2014
W. Legon, Tomokazu Sato, A. Opitz, Jerel K. Mueller, Aaron J. Barbour, A. Williams, W. J. Tyler   +6 more
semanticscholar   +2 more sources

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

SERBP1-PCIF1 complex-controlled m6Am modification in glutamatergic neurons of the primary somatosensory cortex is required for neuropathic pain in mice. [PDF]

Nat Commun
Huang Y, Ma G, Xie S, Wei R, Liu Y, Zeng Y, Zhao Y, Wang Q, Yang L, Huang H, Hao L, Zhao X, Wang H, Shen W, Wong SSC, Cao JL, Tao YX, Pan ZQ.   +17 more
europepmc   +1 more source

High‐Resolution Single‐Neuron Reconstruction Analysis in Golgi‐Stained Brain Tissues

Cell Proliferation, EarlyView.
SNR‐Golgi, a semi‐automated single−neuron$$ \mathrm{single}-\mathrm{neuron} $$ three‐dimensional reconstruction strategy for Golgi−stained samples$$ \mathrm{Golgi}-\mathrm{stained}\ \mathrm{samples} $$, which integrates background denoising$$ \mathrm{background}\ \mathrm{denoising} $$, single‐neuron extraction and branch repair,$$ \mathrm{branch ...
Qiaowei Tang, Binfu Fan, Xiaoqing Cai, Zhiming Shen, Jichao Zhang, Jun Hu, Jiang Li, Ying Zhu   +7 more
wiley   +1 more source

Modeling of Blood Flow Dynamics in Rat Somatosensory Cortex. [PDF]

Biomedicines
Battini S, Cantarutti N, Kotsalos C, Roussel Y, Cattabiani A, Arnaudon A, Favreau C, Antonel S, Markram H, Keller D.   +9 more
europepmc   +1 more source

Behavioral Choice-related Neuronal Activity in Monkey Primary Somatosensory Cortex in a Haptic Delay Task

, 2012
Liping Wang, Xianchun Li, Steven S. Hsiao, Mark Bodner, Fred A. Lenz, Yongdi Zhou   +5 more
openalex   +1 more source