Results 171 to 180 of about 159,461 (344)

Intersectin‐1 enhances calcium‐dependent replenishment of the readily releasable pool of synaptic vesicles during development

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During development, Intersectin‐1 (Itsn1) translocates near voltage‐gated calcium channels (VGCCs) to enhance Ca2+‐dependent replenishment of readily releasable synaptic vesicles (SVs). In the presynaptic terminal, SVs undergo a cycle involving formation (step 1), docking (step 2), exocytosis (step 3), endocytosis (step 4) and ...
Yi‐Mei Yang   +13 more
wiley   +1 more source

Human brain imaging with high‐density electroencephalography: Techniques and applications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Recent technological advances have elevated high‐density electroencephalography (hdEEG) to the status of a reliable neuroimaging tool. This technique measures scalp potentials with high temporal resolution, which permits the non‐invasive detection and analysis of neural oscillations.
Marco Marino, Dante Mantini
wiley   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Figure depicts the key finding from this study. While loss of all dynamins severely debilitates synaptic vesicle retrieval following repetitive activity, retrieval and recycling of individual synaptic vesicles following spontaneous fusion or sparse stimulation are minimally affected.
Olusoji A. T. Afuwape   +4 more
wiley   +1 more source

GluN2C/D‐containing NMDA receptors enhance temporal summation and increase sound‐evoked and spontaneous firing in the inferior colliculus

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Here, we find that GluN2D‐containing NMDA receptors (NMDARs) are expressed by most vasoactive intestinal peptide neurons in the inferior colliculus (IC). These receptors are less susceptible to Mg2+ blockade compared to GluN2A/B‐containing NMDARs, allowing ions to flow at resting membrane potential.
Audrey C. Drotos   +3 more
wiley   +1 more source

Control of action potential afterdepolarizations in the inferior olive by inactivating A‐type currents through KV4 channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend KV4 channel availability regulates inferior olive action potential duration. The durations of action potentials in inferior olive neurons (blue) depend strongly on preceding membrane potential, with afterdepolarizations varying over the physiological range by almost two orders of magnitude (open circles). Voltage clamp recordings
Ziyad W. Sultan   +2 more
wiley   +1 more source

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