Results 11 to 20 of about 309,846 (286)

Eph and ephrin signaling in the development of the central auditory system

Developmental Dynamics, Volume 252, Issue 1, Page 10-26, January 2023., 2023
Abstract Acoustic communication relies crucially on accurate interpretation of information about the intensity, frequency, timing, and location of diverse sound stimuli in the environment. To meet this demand, neurons along different levels of the auditory system form precisely organized neural circuits.
Jakub Krasewicz, Wei‐Ming Yu
wiley   +1 more source

Wiring the senses: Factors that regulate peripheral axon pathfinding in sensory systems

Developmental Dynamics, Volume 252, Issue 1, Page 81-103, January 2023., 2023
Abstract Sensory neurons of the head are the ones that transmit the information about the external world to our brain for its processing. Axons from cranial sensory neurons sense different chemoattractant and chemorepulsive molecules during the journey and in the target tissue to establish the precise innervation with brain neurons and/or receptor ...
Gemma Nomdedeu‐Sancho, Berta Alsina
wiley   +1 more source

Pain‐autonomic measures reveal nociceptive sensitization in complex regional pain syndrome

European Journal of Pain, Volume 27, Issue 1, Page 72-85, January 2023., 2023
Abstract Background Allodynia and hyperalgesia are common signs in individuals with complex regional pain syndrome (CRPS), mainly attributed to sensitization of the nociceptive system. Appropriate diagnostic tools for the objective assessment of such hypersensitivities are still lacking, which are essential for the development of mechanism‐based ...
Paulina S. Scheuren, Iara De Schoenmacker, Jan Rosner, Florian Brunner, Armin Curt, Michèle Hubli   +5 more
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex

Glia, Volume 71, Issue 2, Page 187-204, February 2023., 2023
Main Point Loss of oligodendrocyte ErbB receptor signaling leads to A1 hypomyelination, reduced PV expression and density of PV+ neurons and synapses, hypoconnectivity of inhibitory circuits and shift of the E/I balance towards excitation. Abstract For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination
Beatriz C. Borges, Xiangying Meng, Patrick Long, Patrick O. Kanold, Gabriel Corfas   +4 more
wiley   +1 more source

Alterations in microglial morphology concentrate in the habitual sleeping period of the mouse

Glia, Volume 71, Issue 2, Page 366-376, February 2023., 2023
Main Points We found regional differences of microglial morphology between the somatosensory cortex (SC), hippocampus (HC) and basal forebrain (BF). Cortical‐, but not HC‐ or BF microglial cell sizes negatively correlate with non‐REM sleep slow wave activity.
Sarah Katharina Steffens, Tarja Helena Stenberg, Henna‐Kaisa Margareta Wigren   +2 more
wiley   +1 more source

High frequency repetitive transcranial magnetic stimulation to the left dorsolateral prefrontal cortex modulates sensorimotor cortex function in the transition to sustained muscle pain [PDF]

, 2019
Based on reciprocal connections between the dorsolateral prefrontal cortex (DLPFC) and basal-ganglia regions associated with sensorimotor cortical excitability, it was hypothesized that repetitive transcranial magnetic stimulation (rTMS) of the left ...
De Martino, Enrico, Graven-Nielsen, Thomas, Petrini, Laura, Schabrun, Siobhan M., Seminowicz, David A.   +4 more
core   +3 more sources

A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor learning

Glia, Volume 71, Issue 2, Page 415-430, February 2023., 2023
Main Points A subset of OPCs do not express Olig2, of which population peaks in the juvenile brain while wanes with age. Plastic changes of the brain by acute injuries or complex motor learning stop the expression of Olig2 in OPCs. Abstract Oligodendrocyte precursor cells (OPCs) are uniformly distributed in the mammalian brain; however, their function ...
Li‐Pao Fang, Qing Liu, Erika Meyer, Anna Welle, Wenhui Huang, Anja Scheller, Frank Kirchhoff, Xianshu Bai   +7 more
wiley   +1 more source

Experimental muscle hyperalgesia modulates sensorimotor cortical excitability, which is partially altered by unaccustomed exercise [PDF]

, 2018
Impaired corticomotor function is reported in patients with lateral epicondylalgia, but the causal link to pain or musculotendinous overloading is unclear.
De Martino, Enrico, Graven-Nielsen, Thomas, Petrini, Laura, Schabrun, Siobhan, Zandalasini, Matteo   +4 more
core   +3 more sources

Abnormal sensorimotor cortex and thalamo-cortical networks in familial adult myoclonic epilepsy type 2: pathophysiology and diagnostic implications [PDF]

, 2022
: Familial adult myoclonic epilepsy type 2 is a hereditary condition characterized by cortical tremor, myoclonus and epilepsy. It belongs to the spectrum of cortical myoclonus and the sensorimotor cortex hyperexcitability represents an important ...
Bilo, Leonilda, Coppola, Antonietta, Dubbioso, Raffaele, Esposito, Marcello, Manganelli, Fiore, Striano, Pasquale, Tomasevic, Leo   +6 more
core   +1 more source