Results 271 to 280 of about 70,756 (327)

Control of action potential afterdepolarizations in the inferior olive by inactivating A‐type currents through KV4 channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend KV4 channel availability regulates inferior olive action potential duration. The durations of action potentials in inferior olive neurons (blue) depend strongly on preceding membrane potential, with afterdepolarizations varying over the physiological range by almost two orders of magnitude (open circles). Voltage clamp recordings
Ziyad W. Sultan   +2 more
wiley   +1 more source

Human self and Neurosurgery: Advances and insights from Geneva. [PDF]

open access: yesBrain Spine
Al Awadhi A   +12 more
europepmc   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Differential impacts of social isolation and enriched environment on multi-sensory brain-wide functionality and network segregation. [PDF]

open access: yesNat Commun
You T   +11 more
europepmc   +1 more source

Paired corticospinal‐motoneuronal stimulation enhances ballistic motor learning and corticospinal plasticity in older adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The first part of this experimental study showed that late adulthood (adults aged 65–75 years) is associated with reduced motor performance and learning of simple vigorous finger movements. The second part of the study shows that ballistic motor learning can be improved in older adults when a practice session is preceded by a ...
Jonas Rud Bjørndal   +5 more
wiley   +1 more source

KCC2 enhancers normalize reflex responses and improve locomotor function after chronic spinal cord injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In the intact spinal cord, KCC2 maintains chloride homeostasis, ensuring effective GABAergic inhibition required for normal reflexes and locomotor control (left). Following spinal cord injury, KCC2 is downregulated, weakening inhibitory signaling and leading to dysregulated reflex activity and impaired locomotion (middle ...
Jadwiga N. Bilchak   +3 more
wiley   +1 more source

A Model of Body Perception Disturbances in Chronic Limb Pain: The Predictive Role of Kinesiophobia, Depersonalization and Symptom Severity

open access: yesEuropean Journal of Pain, Volume 29, Issue 9, October 2025.
ABSTRACT Background Body Perception Disturbances (BPD) are common in chronic limb pain conditions characterised by negative feelings toward the limb and a reduced sense of agency. Prior research has focused on isolated associations between psychological factors, pain hypersensitivity and BPD. Therefore, an integrated examination of the interconnections
Hana Karpin   +3 more
wiley   +1 more source

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