A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Advanced Science, EarlyView.Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
The Correlative Analysis of Amplitude-temporal Characteristics of Evoked Potentials of Brain Cortex in Sportsmen [PDF]
, 2017 The article considers the correlative analysis of amplitude-temporal characteristics of evoked potentials of brain cortex in sportsmen of playing kinds of sport and athletes at perception and processing of significant information “What” and “Where” in ...
Poruchynska, T. (Tеtiana) +4 more
core +2 more sources
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Suspected Somatosensory Evoked Potentials Pacing Atria During Cerebral Bypass Surgery: A Case Report
Case Reports in AnesthesiologySomatosensory evoked potentials are commonly utilized during surgery to assess the function of the central nervous system. We present a case of a 48-year-old female patient undergoing cerebral bypass surgery who was noted to have reproducible ...
Denise S. Abdulahad, Justin Pachuski
doaj +1 more source
Frontiers in Surgery, 2021 Background: Intraoperative neurophysiological monitoring (IONM) has been widely applied in brain vascular surgeries to reduce postoperative neurologic deficit (PND).
Dougho Park +9 more
doaj +1 more source
Object-guided Spatial Attention in Touch: Holding the Same Object with Both Hands Delays Attentional Selection [PDF]
, 2009 Previous research has shown that attention to a specific location on a uniform visual object spreads throughout the entire object. Here we demonstrate that, similar to the visual system, spatial attention in touch can be object guided.
Bettina Forster +6 more
core +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Interdisciplinary Neurosurgery, 2023 Objective: Intraoperative neurophysiological monitoring in intramedullary spinal cord tumor removal surgery helps surgeons detect early warning signs of postoperative nerve damage, in order to reduce or prevent permanent neuron injury.
Minh Anh Nguyen +4 more
doaj +1 more source
Altered stimulus frequency and intensity dependence of the somatosensory evoked potential in rats after acute application of two mitochondrial toxins [PDF]
, 2009 Mitochondrial toxins are a special group of toxicants with nervous system ef TRACT - fects. The resulting nervous system damage could be detected and followed-up by means of functional biomarkers but these still have to be worked out.
Bankó, S., Papp, András, Takács, Sz.
core +1 more source
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
, 2009 Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G. +2 more
core +2 more sources