Results 31 to 40 of about 23,142 (208)

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Applications and Challenges of Auditory Brain‐Computer Interfaces in Objective Auditory Assessments for Pediatric Cochlear Implants

Exploration, EarlyView.
Auditory brain‐computer interface connects the brain with external devices and decodes neural signals related to auditory perception. Time‐domain and frequency‐domain analyses are commonly used to identify biomarkers associated with auditory rehabilitation, such as cortical auditory evoked potentials and mismatch negativity.
Qi Zheng, Yubo Wu, Jianing Zhu, Kunyun Feng, Yanru Bai, Guoping Li, Guangjian Ni   +6 more
wiley   +1 more source

Research progress on the mechanisms of pain empathy

Ibrain, EarlyView.
This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu, Siwei Wang, Yan Yan, Bangyong Qin, Qingxiang Mao, Jie Yuan   +5 more
wiley   +1 more source

Benign Idiopathic Myoclonus: A New Clinical Entity?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus is a brief shock‐like, involuntary movement, which can be distinguished in physiologic, essential, epileptic, and symptomatic, according to its etiology. Physiologic myoclonus typically occurs in healthy people without disability or progression.
Giorgia Sciacca, A.M. Madelein van der Stouwe, Sterre van der Veen, Hendriekje Eggink, Martje E. van Egmond, Jan Willem J. Elting, Marina A.J. Tijssen   +6 more
wiley   +1 more source

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

Aging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik, Ádám Nyúl‐Tóth, Rafal Gulej, Roland Patai, Tamas Kiss, Jordan Delfavero, Raghavendra Y. Nagaraja, Priya Balasubramanian, Santny Shanmugarama, Anna Ungvari, Siva Sai Chandragiri, Kiana Vali Kordestan, Mark Nagykaldi, Peter Mukli, Andriy Yabluchanskiy, Sharon Negri, Stefano Tarantini, Shannon Conley, Tae Gyu Oh, Zoltan Ungvari, Anna Csiszar   +20 more
wiley   +1 more source

The method of loci in the context of psychological research: A systematic review and meta‐analysis

British Journal of Psychology, EarlyView.
Abstract This systematic review and meta‐analysis aimed to evaluate (1) the effectiveness of the method of loci (MoL) in enhancing recall in adults, (2) its underlying cognitive mechanisms, and (3) its neurobiological correlates. Studies on adult populations were included from multiple databases.
Jan Ondřej
wiley   +1 more source

Ligand bias and inverse agonism on 5‐HT2A receptor‐mediated modulation of G protein activity in post‐mortem human brain

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Whereas biased agonism on the 5‐HT2A receptor has been ascribed to hallucinogenic properties of psychedelics, no information about biased inverse agonism on this receptor is available. In schizophrenia, increased 5‐HT2A receptor constitutive activity has been suggested, highlighting the therapeutic relevance of inverse ...
Itziar Muneta‐Arrate, Patricia Miranda‐Azpiazu, Igor Horrillo, Rebeca Diez‐Alarcia, J. Javier Meana   +4 more
wiley   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Tremor as an intrinsic feature of juvenile myoclonic epilepsy

Epilepsia, Volume 66, Issue 3, Page e47-e53, March 2025.
Abstract We aim to understand whether tremor may be an intrinsic feature of juvenile myoclonic epilepsy (JME) and whether individuals with JME plus tremor experience a different disease course. Thirty‐one individuals with JME plus tremor (17 females, mean age = 33.9 ± 13.8 years) and 30 age of onset‐ and gender‐matched subjects with JME (21 females ...
Alessia Giugno, Francesco Fortunato, Ilaria Sammarra, Miriam Sturniolo, Enrico Fratto, Iolanda Martino, Rita Nisticò, Antonio Gambardella   +7 more
wiley   +1 more source