Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery oclussion [PDF]
A constant challenge in experimental stroke is the use of appropriate tests to identify signs of recovery and adverse effects linked to a particular therapy. In this study, we used a long-term longitudinal approach to examine the functional brain changes
Barios Heredero, Juan Antonio +6 more
core +2 more sources
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Object-guided Spatial Attention in Touch: Holding the Same Object with Both Hands Delays Attentional Selection [PDF]
Previous research has shown that attention to a specific location on a uniform visual object spreads throughout the entire object. Here we demonstrate that, similar to the visual system, spatial attention in touch can be object guided.
Bettina Forster +6 more
core +1 more source
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou +7 more
wiley +1 more source
EEG During Pedaling: Evidence for Cortical Control of Locomotor Tasks [PDF]
Objective: This study characterized the brain electrical activity during pedaling, a locomotor-like task, in humans. We postulated that phasic brain activity would be associated with active pedaling, consistent with a cortical role in locomotor tasks ...
Gourab, Krishnaj +3 more
core +2 more sources
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng +14 more
wiley +1 more source
Pudendal somatosensory evoked potentials in normal women
OBJECTIVE: Somatosensory evoked potential (SSEP) is an electrophysiological test used to evaluate sensory innervations in peripheral and central neuropathies.
Geraldo A. Cavalcanti +6 more
doaj +1 more source
Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin +2 more
wiley +1 more source
Quantifying the effect of isoflurane and nitrous oxide on somatosensory-evoked potentials
Anaesthetic techniques may have a significant effect on intraoperative-evoked potentials (EP). The present study is designed to compare Propofol anaesthesia with Isoflurane (with or without nitrous oxide) during intraoperative somatosensory-evoked ...
Usha Devadoss, S Babu, V T Cherian
doaj +1 more source
Consequences of subacute intratracheal exposure of rats to cadmium oxide nanoparticles: Electrophysiological and toxicological effects [PDF]
Cadmium is a metal used in various industrial applications, whereby exposure to Cd-containing fumes is likely. The submicron sized particles in the fumes represent an extra risk due to their high mobility within the organism and high surface area ...
Horváth, Edina +7 more
core +1 more source

