Somatotopy in the Human Somatosensory System [PDF]
Previous functional magnetic resonance imaging (fMRI) studies have demonstrated digit somatotopy in primary somatosensory cortex (SI), and even shown that at high spatial resolution it is possible to resolve within-digit somatotopy. However, fMRI studies
Rosa M. Sanchez Panchuelo+4 more
doaj +7 more sources
Potential mechanisms of acupuncture for neuropathic pain based on somatosensory system [PDF]
Neuropathic pain, caused by a lesion or disease of the somatosensory system, is common and distressing. In view of the high human and economic burden, more effective treatment strategies were urgently needed.
Xin Ma+9 more
doaj +3 more sources
The 'creatures' of the human cortical somatosensory system. [PDF]
Abstract Penfield’s description of the ‘homunculus’, a ‘grotesque creature’ with large lips and hands and small trunk and legs depicting the representation of body-parts within the primary somatosensory cortex (S1), is one of the most prominent contributions to the neurosciences.
Saadon-Grosman N, Loewenstein Y, Arzy S.
europepmc +6 more sources
Aging of the Somatosensory System: A Translational Perspective [PDF]
Balance in the elderly population is a major concern given the often catastrophic and disabling consequences of fall-related injuries. Structural and functional declines of the somatosensory system occur with aging and potentially contribute to postural instability in older adults.
Scott W. Shaffer, Anne Harrison
semanticscholar +6 more sources
Astrocyte and Neuronal Plasticity in the Somatosensory System. [PDF]
Changing the whisker complement on a rodent’s snout can lead to two forms of experience-dependent plasticity (EDP) in the neurons of the barrel cortex, where whiskers are somatotopically represented. One form, termed coding plasticity, concerns changes in synaptic transmission and connectivity between neurons.
Sims RE+3 more
europepmc +8 more sources
Targeting the somatosensory system with AAV9 and AAV2retro viral vectors. [PDF]
Adeno-associated viral (AAV) vectors allow for site-specific and time-dependent genetic manipulation of neurons. However, for successful implementation of AAV vectors, major consideration must be given to the selection of viral serotype and route of ...
Skorput AGJ+8 more
europepmc +2 more sources
Modulation of the human sensorimotor system by afferent somatosensory input: evidence from experimental pressure stimulation and physiotherapy [PDF]
Peripheral afferent input is critical for human motor control and motor learning. Both skin and deep muscle mechanoreceptors can affect motor behaviour when stimulated.
Pavel Hok, Petr Hlustik
doaj +2 more sources
Acute microglia ablation induces neurodegeneration in the somatosensory system. [PDF]
Previous studies have reported that microglia depletion leads to impairment of synapse formation and these cells rapidly repopulate from CNS progenitors.
Rubino SJ+14 more
europepmc +2 more sources
Somatosensory system integrity explains differences in treatment response after stroke. [PDF]
Objective To test the hypothesis that, in the context of robotic therapy designed to enhance proprioceptive feedback via a Hebbian model, integrity of both somatosensory and motor systems would be important in understanding interparticipant differences ...
Ingemanson ML+5 more
europepmc +2 more sources
A hierarchical system through the somatosensory cortex builds representations of touch and of the positions of the limbs in space up through parietal cortex areas 5 and 7b, where the system is interfaced to the visual system for the computations involved in reaching into space and grasping objects.
H. J. Ten Donkelaar+2 more
openaire +2 more sources