Results 121 to 130 of about 17,294,201 (287)

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective.
Dongjun Guo   +4 more
wiley   +1 more source

The somatosensory cortex receives information about motor output

open access: yes
During voluntary movement, the somatosensory system not only passively receives signals from the external world but also actively processes them via interactions with the motor system.
Umeda, Tatsuya   +2 more
core  

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia   +19 more
wiley   +1 more source

Use of the Brain-gauge Somatosensory Assessment for Monitoring Recovery from Concussion: A Case Study

open access: yes, 2018
Objectives: To determine if Brain Gauge somatosensory metrics would adequately reflect an individual’s recovery. Design: Prospective case study of Ms ‘K’.
Tommerdahl, M, Hume, P, King, DA
core   +1 more source

Creativity and its link to epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Sensorimotor Dysfunction Following Anterior Cruciate Ligament Reconstruction- an Afferent Perspective: A Scoping Review

open access: yesInternational Journal of Sports Physical Therapy
# Background Sensorimotor dysfunction is thought to occur following anterior cruciate ligament (ACL) injury which may have implications on future reinjury risk.
Thilina N Vitharana   +2 more
doaj   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

Manifestation of lipopolysaccharide-induced tolerance in neuro-glial primary cultures of the rat afferent somatosensory system. [PDF]

open access: yesInflamm Res, 2021
Nürnberger F   +6 more
europepmc   +1 more source

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