Results 131 to 140 of about 5,453 (264)

Sphingosine-1-phosphate induces pulmonary artery smooth muscle cell proliferation, migration and pulmonary arterial remodeling by modulating sonic hedgehog signaling effector FoxM1. [PDF]

Chin Med J (Engl)
Yan X, Li S, Wang J, Wang Q, Xie X, Li M.   +5 more
europepmc   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Combating orthopedic implant biofilms - SABER (Study on Agitation for Biofilm Eradication and Reduction) evaluates mechanical, sonication, and radiofrequency approaches: a preclinical in vitro study. [PDF]

Acta Orthop
McManus TG, Fort MW, Barrack KE, Ray GS, Sparks MB, McGuire KJ, O'Toole GAO.   +6 more
europepmc   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Synthetic capillary pressure modeling with dipole sonic waves for enhanced reservoir characterization. [PDF]

Sci Rep
Galarza-Alava J, Mendoza-Sanz J.
europepmc   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

Actin-related protein 6 regulates the Hedgehog signaling pathway: Molecular basis for stemness maintenance of hepatoma cells. [PDF]

Cytojournal
Jiao C, Zhu L, Zhu A, Xu X.
europepmc   +1 more source

UBE2O Drives Immune Evasion and Radioimmunotherapy Resistance in Lung Cancer by Degrading CDKL1 to Induce PD‐L1 Transcription

Advanced Science, EarlyView.
UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue, Xiaohua Jie, Zhiwei Liu, Ruoxin Fang, Shuo Wu, Xiaorong Dong, Shuangbing Xu   +6 more
wiley   +1 more source

Effect of toothbrush type on biofilm and periodontal health in orthodontic patients. [PDF]

Bioinformation
Sharma P, Sharma R, Nadkerny V, Sohi HK, V S B, Rebello AA, Mehta M.   +6 more
europepmc   +1 more source

Sonic crystals as tunable noise barriers

, 2016
This work reports an introduction to the topic of wave propagation in sonic crystals and a review of the recent scientific literature. The paper presents the results of some experimental investigations carried out at the University of Bologna by discussing Insertion Loss measurements, measurements performed inside the lattice and sound intensity ...
MORANDI, FEDERICA, MARZANI, ALESSANDRO, DE CESARIS, SIMONA, D'ORAZIO, DARIO, BARBARESI, LUCA, GARAI, MASSIMO   +5 more
openaire   +1 more source