Results 141 to 150 of about 2,042 (179)
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Biomaterials
Periodontitis is a chronic disease caused by bacteria (e.g. Porphyromonas gingivalis, P.gingivalis) that currently lacks effective non-invasive treatment options. Sonodynamic therapy (SDT) is an emerging non-invasive antimicrobial therapeutic strategy.
Gang He, Guoping Li, Suxia Han
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Periodontitis is a chronic disease caused by bacteria (e.g. Porphyromonas gingivalis, P.gingivalis) that currently lacks effective non-invasive treatment options. Sonodynamic therapy (SDT) is an emerging non-invasive antimicrobial therapeutic strategy.
Gang He, Guoping Li, Suxia Han
exaly +3 more sources
Engineering Sonosensitizer‐Derived Nanotheranostics for Augmented Sonodynamic Therapy
SmallAbstractSonodynamic therapy (SDT), featuring noninvasive, deeper penetration, low cost, and repeatability, is a promising therapy approach for deep‐seated tumors. However, the general or only utilization of SDT shows low efficiency and unsatisfactory treatment outcomes due to the complicated tumor microenvironment (TME) and SDT process.
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Sonosensitizers for Sonodynamic Therapy: Current Progress and Future Perspectives
Ultrasound in Medicine & BiologySonodynamic therapy (SDT) is a novel non-invasive treatment method that combines low-intensity ultrasound and sonosensitizers. Compared with photodynamic therapy, SDT has the advantages of deeper tissue penetration, higher accuracy and fewer adverse reactions. Sonosensitizers are essential for the efficacy of SDT. Sonosensitizers have the advantages of
Ting Wang, Meng Du, Zhiyi Chen
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Pancatalytic Tumor Therapy by Ultrasound Activation of Inorganic Sonosensitizers
ChemBioChemPancatalytic therapy (PCT) is a comprehensive framework for disease management through the holistic control of catalytic and quasi‐catalytic processes, including preparation (P) of catalysts, activation (A) of specific bio‐effects, and nontoxic treatment (N) of different diseases.
Furong Cheng, Yu Tian, Yu Chen
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Sonodynamic antitumor effect of a novel sonosensitizer on S180 solid tumor
Biopharmaceutics & Drug Disposition, 2013ABSTRACTPurpose: The purpose of this study was to evaluate the sonodynamically induced antitumor effect of a novel sonosensitizer (DVDMS) in mice bearing sarcoma 180 solid tumors. Methods: In order to determine the optimum timing of ultrasound exposure after administration of DVDMS, a three‐dimensional optical imaging system (IVIS spectrum) was used to
Caifeng, Li +5 more
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Exploring BODIPY derivatives as sonosensitizers for anticancer sonodynamic therapy
European Journal of Medicinal ChemistrySonodynamic therapy (SDT) is an emerging non-invasive and effective therapeutic modality for cancer treatment bearing benefit of deep tissue-penetration in comparison to photo-inspired therapy. However, exploring novel sonosensitizers with high sonosensitivity and desirable biosafety remains a significant challenge.
Xudong Li +8 more
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Multifunctional Porphyrin‐Based Sonosensitizers for Sonodynamic Therapy
Advanced Functional MaterialsAbstractSonodynamic therapy (SDT), as a promising non‐invasive therapeutic modality combining ultrasound (US) and sonosensitizers to produce cytotoxic reactive oxygen species (ROS) for treating deep‐seated tumors, has received increasing attention in recent years.
Jiajun Chen, Qi Zhou, Wenwu Cao
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A sonosensitive diphenylalanine-based broad-spectrum antimicrobial peptide
Nature Biomedical EngineeringThe antimicrobial effect of antimicrobial peptides is typically slow; they can be rapidly biodegraded and often have non-selective toxicity and elaborate sequences. Here we report a short peptide that is activated by ultrasound, that shows high broad-spectrum antibacterial efficiency (>99%) against clinically isolated methicillin-resistant bacteria ...
Xiaoguang Zhang +10 more
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Formulation and Characterization of Sonosensitive Organic Nanoparticles
2021In den pharmazeutischen Wissenschaften scheinen nanoskalige Formulierungen die Antwort auf viele neue Therapie- und Diagnoseansätze zu sein [1]. Über 350 Studien zu verschiedenen Nanopartikelformulierungen und Indikationsgebieten werden derzeit in klinischen Studien durchgeführt, von denen allerdings nur 26 die Phase 3 erreicht haben [2]. Sie sind auch
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A biodegradable theranostic sonosensitizer for afterglow-guided sonodynamic therapy
Acta BiomaterialiaOptical imaging is crucial in biology and medicine, yet fluorescence imaging suffers from poor tissue penetration, low signal-to-background ratio (SBR), and limited sensitivity/specificity. Ultrasound (US) imaging, being a non-invasive and widely used modality for anatomical and functional visualization, offers a promising source of activation for ...
Chunbai Xiang +12 more
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