Mycobacterium leprae genomes from naturally infected nonhuman primates.
Leprosy is caused by the bacterial pathogens Mycobacterium leprae and Mycobacterium lepromatosis. Apart from humans, animals such as nine-banded armadillos in the Americas and red squirrels in the British Isles are naturally infected with M.
Tanvi P Honap +9 more
doaj +1 more source
Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys [PDF]
The TRIM family proteins share a conserved arrangement of three adjacent domains, an N-terminal RING domain, followed by one or two B-boxes and a coiled-coil, which constitutes the tripartite-motif for which the family is named. However, the C-termini of
Farzan, Michael Reynolds +7 more
core +1 more source
Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection. [PDF]
International audienceHuman immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in macaques (MAC) lead to chronic inflammation and AIDS. Natural hosts, such as African green monkeys (AGM) and sooty mangabeys (SM), are protected
Barré-Sinoussi, Françoise +14 more
core +4 more sources
Drivers of disease emergence and spread: Is wildlife to blame? [PDF]
The global focus on wildlife as a major contributor to emerging pathogens and infectious diseases (EIDs) in humans and domestic animals is not based on field, experimental or dedicated research, but mostly on limited surveys of literature, opinion and ...
Kock, R A
core +2 more sources
Patterns of genomic sequence diversity among their simian immunodeficiency viruses suggest that L'Hoest monkeys (Cercopithecus lhoesti) are a natural lentivirus reservoir [PDF]
Recently, we described a novel simian immunodeficiency virus (SIVlhoest) from a wild-caught L'Hoest monkey (Cercopithecus lhoesti) from a North American zoo.
Bibollet-Ruche F. +28 more
core +1 more source
Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV
ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik +5 more
wiley +1 more source
Early adolescent Depo-Provera exposure increases stillbirths in adult sooty mangabeys [PDF]
The 3-month injectable contraceptive medroxyprogesterone acetate (MPA; Depo-Provera) is a synthetic progestin that protects against pregnancy by suppressing ovulation. Studies have focused on the resumption of ovulation after MPA-treatment cessation but neglected potential long-term effects of MPA exposure on future successful reproduction.
Maurand, Cappelletti +4 more
openaire +2 more sources
Decoding HIV‐1 Next Move Through Matrix Protein p17 Quasi‐Species
HIV‐1 mutants expressing clonogenic HIV‐1 matrix protein p17 variants (vp17s) are spreading, increasing their prevalence worldwide. In RNA viruses, quasi‐species are transmitted among hosts, leading to the generation of new master sequences. We developed a next‐generation sequence approach to evaluate the frequency of vp17 quasi‐species in people ...
Serena Messali +7 more
wiley +1 more source
This study shows that young goats outperform sheep in the reversed‐reward contingency task, which is a cognitive test requiring both inhibitory control and cognitive flexibility. The results highlight the importance of cognitive flexibility when solving this type of task, and suggest that the differences between both species may reflect social and ...
Laurie Castro +2 more
wiley +1 more source
An Exploration of DNA Extraction Methods of Fly iDNA for Scalable Biodiversity Monitoring
Metabarcoding of invertebrate‐derived DNA (iDNA) is an excellent tool for assessing terrestrial mammal diversity, but the time and costs associated with sample processing constrain its wider adoption. Our study indicates that the non‐destructive extraction of large pools of entire fly bodies has the potential to streamline and reduce the costs of fly ...
Mueena Jahan +21 more
wiley +1 more source

