Accelerating Biosensor Discovery: A Computationally‐Driven Pipeline for Microplastics Monitoring
A computationally guided pipeline unites molecular simulation, synthetic biology, electrochemical engineering, and machine learning to accelerate biosensor discovery. A Bacillus anthracis carbohydrate‐binding module is used to develop a high‐performance micro‐ and nanoplastics sensor with greatly reduced error and variability.
Gabriel X. Pereira +13 more
wiley +1 more source
This work shows the successful integration of intrinsic bistability into thermoresponsive soft microactuators, fabricated by two‐photon polymerization utilizing the (E)–(Z)‐isomerization of azobenzenes. The bistable behavior accounts for a reversible volume change of Azo_pNIPAM microactuators initiated by light irradiation, at constant ambient ...
Chantal Barwig +13 more
wiley +1 more source
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
“The word is man, man is spiritual community, spiritual community is Sophia”. Gnostic myth and the construction of the author in L. P. Karsavin’s Sophia the earthly and the heavenly [PDF]
«Sophia the earthly and the heavenly» was written by L.P. Karsavin during his transition from medievism to religious philosophy. The text was first published in the third issue of the almanac Sagittarius (1922). It represents a literary hoax: an «unknown»
Nataly Vaganova
doaj +1 more source
Taming the Floods: Using an Intellectual History of Chinese Hydraulic Thought to Address Contemporary Issues in China’s Water Governance [PDF]
China’s current hydraulic systems are in a state of atrophy, caused by sustained damage over centuries to infrastructure that has changed very little. Added to an already weak infrastructure is a relatively new crisis of water scarcity, which is forcing ...
Danison, Sophia Rose
core +1 more source
ABSTRACT Background Classified as carcinogenic to humans by the International Agency for Research on Cancer, aluminum production has been transitioning towards lower polycyclic aromatic hydrocarbon‐emitting prebake smelters. This study explored the risk of cancer and mortality over 20 years follow‐up among a cohort of aluminum prebake smelter workers ...
Natasha Kinsman +7 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
How is EU cooperation on the Covid-19 crisis perceived in member states? CEPS Commentary 21 April [PDF]
The crisis caused by the spread of Covid-19 has demonstrated how difficult European cooperation can be, especially in policy areas where the EU has only a legal competence to support member states.
Blockmans, Steven, Russack, Sophia
core
Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data
ABSTRACT A molecular diagnosis is currently achievable in approximately 50% of patients assessed by clinical geneticists at tertiary care centres. Next‐Generation Sequencing Panels contain a defined group of genes associated with a clinically defined set of phenotypes.
Ana Acosta Bedón +10 more
wiley +1 more source
Greek Monetary Economics in Retrospect: The Adventures of the Drachma [PDF]
This paper enumerates the adventures of the drachma step by step, dividing its story into seven parts. Specifically, its main purpose is to present some historical perspective on the behaviour of the monetary and fiscal policies pursued in Greece during ...
Sophia
core

