Results 51 to 60 of about 2,159 (285)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
History of Thought and History of Humankind in Plato’s Protagoras
PeithoIn Plato’s Protagoras, prompted by Socrates, Protagoras grapples with the complex problem of the nature of the sophistike techne that he professes. To clarify the nature of his teaching, he reconstructs a history of his discipline, identifying a series ...
Michele Corradi
doaj +1 more source
Peter Redpath’s Philosophy of History [PDF]
Studia Gilsoniana, 2016 Peter Redpath is a distinguished historian of philosophy. He believes that the best way to acquire a philosophical education is through the study of philosophy’s history.
Curtis L. Hancock
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
On the Sophistry of A Modern Humanistsic Discourse – Traditions, Postcolonial Implications, Consequences [PDF]
, 2014 Celem artykułu jest analiza współczesnego dyskursu humanistycznego w Polsce, w którym szczególną rolę odgrywają: kondycja postkolonialna, trzecia sofistyka i zaplecze ideologiczne systemu komunistycznego.
Skwara, Marta, Skwara, Michał
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Archetype of sophistry in Pavlo Tychyna's creative literal activity [PDF]
, 2016 In this article the archetype of sophistry in the literature of Pavlo Tychyna is shown. In the poet’s poetry sophistry is represented as a literal credo of poet’s thought unity with the world o f nature in which he establishes a dialogue with a human,
Ковальчук, Наталія Дмитрівна
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source