Consistent RNA expression and RNA modification patterns in cardiotoxicity induced by Matrine and Evodiamine. [PDF]
Fang G +5 more
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Screening of Medicinal Herbs Identifies <i>Cimicifuga foetida</i> and Its Bioactive Component Caffeic Acid as SARS-CoV-2 Entry Inhibitors. [PDF]
Liu CH +5 more
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Five matrine-type alkaloids from Sophora tonkinensis
Journal of Natural Medicines, 2021Five matrine-type alkaloids (1‒5) including two new compounds (1 and 3) and a new natural product (2) were isolated from the roots of Sophora tonkinesis. Their structures were identified by extensive spectroscopic analysis (UV, IR, HRESIMS and NMR). The absolute configurations of 2 and 3 were determined by X-ray diffraction.
Qing, Tang +9 more
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Bioactive quinolizidine alkaloids from Sophora tonkinensis
China Journal of Chinese Materia Medica, 2016Twelve quinolizidine alkaloids were isolated from Sophora tonkinensis by means of silica gel, preparative MPLC, and preparative HPLC. On analysis of NMR spectroscopic data, their structures were established as 3-(4-hydroxyphenyl)-4-(3-methoxy-4-hydroxyphenyl)-3,4-dehydroquinolizidine(1), lanatine A(2), cermizines C(3), senepodines G(4), senepodines H(5)
Yan, Zhang +5 more
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Pectic polysaccharides from Radix Sophorae Tonkinensis exhibit significant antioxidant effects
Carbohydrate Polymers, 2021Two pectic polysaccharides (WRSP-A2b and WRSP-A3a) have been obtained from Radix Sophorae Tonkinensis and comparatively investigated in terms of their physical properties and antioxidant activities. Monosaccharide composition, FT-IR, NMR and enzymatic analyses indicate that both WRSP-A2b (13.6 kDa) and WRSP-A3a (44.6 kDa) consist of homogalacturonan ...
Xin, Ning +8 more
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A new flavonol from Sophora tonkinensis
Journal of Asian Natural Products Research, 2007A new flavonol, tonkinensisol, was isolated from the roots of Sophora tonkinensis, together with three known compounds named as bayin, vitexin and lupeol. Their structures were elucidated on the basis of spectroscopic evidence. Additionally, tonkinensisol showed moderate cytotoxicity suppressing the proliferation of HL-60 cells in vitro.
Y-H, Deng +5 more
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Studies on chemical constituents of rhizomes of Sophora tonkinensis
China Journal of Chinese Materia Medica, 2016Thirteen compounds were isolated from the 95% aqueous EtOH extract of the rhizomes of Sophora tonkinensis by a combination of various chromatographic techniques including column chromatography over silica gel, Sphadex LH-20, MCI, ODS, and semi-preparative HPLC.Their structures were elucidated as 1-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)ethanone(1),
Qi-Ming, Pan +4 more
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Three new alkaloids from the roots of Sophora tonkinensis
Journal of Natural Medicines, 2019A new β-carboline alkaloid (1) and two new matrine-type alkaloids (2 and 3), together with two known alkaloids (4 and 5), were isolated from the roots of Sophora tonkinensis. The new structures were elucidated via extensive analyses of the spectroscopic data (IR, UV, HRESIMS, NMR) and X-ray crystallography.
Chun, Wu +6 more
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Isoprenylated flavonoids from the roots of Sophora tonkinensis
Phytochemistry Letters, 2008Abstract Two new isoprenylated flavanones, tonkinochromanes J ( 1 ) and K ( 2 ), and a new isoprenylated dihydrochalcone, tonkinochromane L ( 3 ), were isolated from the roots of Sophora tonkinensis along with four known compounds ( 4-7 ). Their structures were determined by means of spectroscopic analyses, including HRMS, IR, 1 H and 13 C NMR ...
Xing-Nuo Li +8 more
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[Studies on the alkaloids of radix Sophorae Tonkinensis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1990Six alkaloids were isolated from Radix Sophorae Tonkinensis. On the basis of spectrometric analysis and physico-chemical constants they were identified as (I) (+)-matrine, (II) (-)-cytisine, (III) (+)-matrine N-oxide, (IV)(+)-sophocarpine N-oxide, (V)(+)-sophoramine and (VI) (+)-sophoranol respectively.
J H, Dou, J S, Li, W M, Yan
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