An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes [PDF]
Stem Cell Research & Therapy, 2019 Background Cardiotoxicity remains an important concern in drug discovery and clinical medication. Meanwhile, Sophora tonkinensis Gapnep. (S. tonkinensis) held great value in the clinical application of traditional Chinese medicine, but cardiotoxic ...
Ruiying Wang +9 more
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Mineral element contents and gene expression in Sophora tonkinensis during florescence [PDF]
Biotechnology & Biotechnological Equipment, 2021 As a medicinal plant, Sophora tonkinensis is mainly distributed in Guangxi, Yunnan, Guizhou and northern Vietnam. In recent years, due to the strong demand for S. tonkinensis, wild resources have become decreased, which has placed great pressure on their
Lin-xuan Li +9 more
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Anti-Inflammatory Effects of 6,8-Diprenyl-7,4′-dihydroxyflavanone from Sophora tonkinensis on Lipopolysaccharide-Stimulated RAW 264.7 Cells [PDF]
Molecules, 2016 The anti-inflammatory effects and molecular mechanism of 6,8-diprenyl-7,4′-dihydroxyflavanone (DDF), one of the flavanones found in Sophora tonkinensis, were assessed in vitro through macrophage-mediated inflammation in the present study.
Hee-Sung Chae +5 more
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Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37 [PDF]
MoleculesChemical investigation of Penicillium sp. GDGJ-N37, a Sophora tonkinensis-associated fungus, yielded two new azaphilone derivatives, N-isoamylsclerotiorinamine (1) and 7-methoxyl-N-isoamylsclerotiorinamine (2), and four known azaphilones (3–6), together ...
Lili Huang +9 more
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Comparative chloroplast genomes of Sophora species: identification of variable DNA markers and phylogenetic relationships within the genus [PDF]
BMC Plant BiologyBackgroud Sophora L. is a medicinally significant genus within Papilionoideae (Fabaceae), renowned for its medicinal, ecological, and economic importance.
Na Duan, Dafu Ru, Bingbing Liu
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Multi-omics analysis uncovers the transcriptional regulatory mechanism of magnesium Ions in the synthesis of active ingredients in Sophora tonkinensis [PDF]
Scientific ReportsMagnesium (Mg) plays a pivotal role as an essential component of plant chlorophyll and functions as a critical coenzyme. However, research exploring the regulatory mechanisms of magnesium ions on the synthesis of secondary metabolites is still in its ...
Zhu Qiao +8 more
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Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice [PDF]
Frontiers in Pharmacology, 2016 This study investigated the active principles, hypoglycemic activity and potential mechanisms of the flavonoid rich extract from Sophora tonkinensis Gagnep. (SS-EtOAc) in KK-Ay diabetic mice.
Mi Huang +11 more
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Characterization of the complete chloroplast genome of Sophora tonkinensis Gagnep. [PDF]
Mitochondrial DNA. Part B. Resources, 2019 In this study, the complete chloroplast (cp) genome of Sophora tonkinensis Gagnep. was determined through Illumina sequencing method. The complete chloroplast genome of S. tonkinensis was 155,640 bp in length and contained a pair of IR regions (25,925 bp)
Wenlong Zhang +4 more
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Trifolirhizin: A Phytochemical with Multiple Pharmacological Properties [PDF]
MoleculesTrifolirhizin is an important flavonoid glycoside reported from the roots of medicinal plants such as Astragalus membranaceus, Sophora tonkinensis, Ononis vaginalis, Euchresta formosana, Sophora Subprostrate, Ononis spinose, and Sophora flavescens. It is
Varun Jaiswal, Hae-Jeung Lee
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Correction: Chae, H.S., et al. Anti-Inflammatory Effects of 6,8-Diprenyl-7,4′-dihydroxyflavanone from Sophora tonkinensis on Lipopolysaccharide-Stimulated RAW 264.7 Cells. Molecules. 2016, 21, 1049. [PDF]
Molecules, 2016 n ...
Hee-Sung Chae +5 more
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