Greater Efficiency Observed 12 Months Post-Implementation of an Automatic Tube Sorting and Registration System in a Core Laboratory/ Veća Efikasnost Uočena 12 Meseci Posle Implementacije Sistema za Automatsko Sortiranje i Registrovanje Uzoraka u Centralnoj Laboratoriji [PDF]
Fatma Uçar +6 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Empirical Evaluation of Unoptimized Sorting Algorithms on 8-Bit AVR Arduino Microcontrollers. [PDF]
Golonka J, Krużel F.
europepmc +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Nottingham Hip Fracture Score Versus Surgical Outcome Risk Tool in Predicting 30-Day Mortality in Hip Fracture Patients in a District General Hospital in the United Kingdom. [PDF]
Prasad S, Obidigbo B.
europepmc +1 more source
Editorial Commentary: Determining the Effect of Hepatitis C on Mortality: Sorting the Signal From the Noise [PDF]
Kathleen M. Rose
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