Results 211 to 220 of about 3,235,300 (271)

FastGA: Fast Genome Alignment

open access: yes
Myers G, Durbin R, Zhou C.
europepmc   +1 more source

Weighing Costs and Benefits of Delay and the Acceptance of Two Decision Support Tools in Mental Health Care: Scoping Study Using Quantitative and Qualitative Data.

open access: yesJMIR Hum Factors
McKenna S   +11 more
europepmc   +1 more source

Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models

open access: yesNature Communications, 2023
Approximately 10% of Cystic Fibrosis (CF) patients, particularly those with CF transmembrane conductance regulator (CFTR) gene nonsense mutations, lack effective treatments.
Tuo Wei, Yehui Sun, Qiang Cheng
exaly   +2 more sources

Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing

open access: yesNature Nanotechnology, 2020
CRISPR–Cas gene editing and messenger RNA-based protein replacement therapy hold tremendous potential to effectively treat disease-causing mutations with diverse cellular origin. However, it is currently impossible to rationally design nanoparticles that
Qiang Cheng, Tuo Wei, Lukas Farbiak
exaly   +2 more sources

Spleen SORT LNP Generated in situ CAR T Cells Extend Survival in a Mouse Model of Lymphoreplete B Cell Lymphoma

open access: yesAngewandte Chemie - International Edition, 2023
Chimeric Antigen Receptor (CAR) T cell immunotherapy is revolutionizing treatment for patients suffering from B-cell lymphoma (BL). However, the current method of CAR T cell production is complicated and expensive, requiring collection of patient blood ...
Daniel J Siegwart
exaly   +2 more sources
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Deep OC-Sort: Multi-Pedestrian Tracking by Adaptive Re-Identification

International Conference on Information Photonics, 2023
Motion-based association for Multi-Object Tracking (MOT) has recently re-achieved prominence with the rise of powerful object detectors. Despite this, little work has been done to incorporate appearance cues beyond simple heuristic models that lack ...
Gerard Maggiolino   +3 more
semanticscholar   +1 more source

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