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Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing

open access: yesNature Nanotechnology, 2020
CRISPR–Cas gene editing and messenger RNA-based protein replacement therapy hold tremendous potential to effectively treat disease-causing mutations with diverse cellular origin. However, it is currently impossible to rationally design nanoparticles that
Qiang Cheng, Tuo Wei, Lukas Farbiak
exaly   +2 more sources

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