This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu +7 more
wiley +1 more source
Artificial Intelligence-Enhanced Multi-Algorithm R Shiny Application for Predictive Modeling and Analytics: Case Study of Alzheimer Disease Diagnostics. [PDF]
Wenzheng H +4 more
europepmc +1 more source
Natural Products with Potential for the Treatment of Pain: Global Evidence from the NAPRALERT Database. [PDF]
Graham JG +5 more
europepmc +1 more source
scATAC-Ref: a reference of scATAC-seq with known cell labels in multiple species. [PDF]
Qian FC +11 more
europepmc +1 more source
Veterans health administration national cardiac device surveillance program: Structured, centralized remote monitoring for cardiovascular implantable electronic devices to improve quality of care. [PDF]
Dhruva SS +5 more
europepmc +1 more source
Successful adoption of an advance care planning evidence-based practice: impact of clinical champion and site factors. [PDF]
Magid KH +7 more
europepmc +1 more source
Summary of the National Cancer Institute 2023 Virtual Workshop on Medical Image De-identification-Part 1: Report of the MIDI Task Group - Best Practices and Recommendations, Tools for Conventional Approaches to De-identification, International Approaches to De-identification, and Industry Panel on Image De-identification. [PDF]
Clunie D +13 more
europepmc +1 more source
Monthly-Resolved Cave Proxy Evidence for Northward Gulf Stream Migration During the Little Ice Age
Forman E +10 more
europepmc +1 more source
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