Results 61 to 70 of about 72,292 (263)

Quantitative mechanisms of DNA damage sensing and signaling

, 2020
DNA damage occurs abundantly during normal cellular proliferation. This necessitates that cellular DNA damage response and checkpoint pathways monitor the cellular DNA damage load and that DNA damage signaling is quantitative.
Bantele, S., Pfander, B.
core   +1 more source

Smart Charging With Hourly Pricing as Policy Intervention: Reducing Costs and Grid Congestion for Promoting Electric Vehicles in Developing Countries

Energy Science &Engineering, EarlyView.
Smart charging with hourly pricing optimizes electric vehicle (EV) charging in developing countries, reducing EV owner costs by 30% and easing grid congestion. Using an agent‐based energy management system, the study shows dynamic pricing effectively shifts charging to off‐peak hours, enhancing grid stability and supporting sustainable EV adoption in ...
Maha Iftikhar, Kashif Imran, Farah Ul Ain, Abdul Kashif Janjua, Rimsha Razaq, Sohail Khan, Arqam Ilyas, Shahbaz Ul Haq, Muhammad Akmal   +8 more
wiley   +1 more source

Synthesis, secretion, and perception of abscisic acid regulates stress responses in \u3ci\u3eChlorella sorokiniana\u3c/i\u3e [PDF]

, 2018
Abscisic acid (ABA) is a phytohormone that has been extensively characterized in higher plants for its roles in seed and bud dormancy, leaf abscission, and stress responses.
Alvarez, Sophie, Beckeris, Richard, Cahoon, Rebecca E., Eyun, Seong-il, Jia, Qidong, Khasin, Maya, Nickerson, Kenneth, Riekhof, Wayne R., Riethoven, Jean-Jack   +8 more
core   +1 more source

Monotonicity of Fitness Landscapes and Mutation Rate Control [PDF]

, 2016
A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear advantage of using variable mutation rates as a control parameter to optimise the performance of ...
A Kong, AE Eiben, AE Nix, AF Agrawal, AF Agrawal, Alastair Channon, BMR Stadler, CA Aktipis, CA Aktipis, CG Knight, Christopher G. Knight, DR Rokyta, Elizabeth Aston, FC Adams, G Badis, HA Orr, HA Orr, HA Orr, HA Orr, HA Orr, I Bjedov, ID Falco, J Cervantes, J He, JA Visser de, JM Smith, John Aston, L Hadany, M Kimura, MJ McDonald, O Tenaillon, P Schuster, R Ahlswede, R Kassen, R Krašovec, R Poli, RA Fisher, RC MacLean, RJ Woods, Rok Krašovec, Roman V. Belavkin, RS Galhardo, S Banach, S Böttcher, S Collins, S Mazurkiewicz, SJ Freeland, T Bataillon, T Jansen, V Mustonen, WH Zhong, Y Ram   +51 more
core   +4 more sources

AI‐enabled biomimetic flexible pressure sensors for high‐precision gait monitoring and rehabilitation assessment

FlexMat, EarlyView.
A biomimetic multilayer capacitive sensor‐integrated insole enables high‐resolution plantar pressure mapping for intelligent gait analysis. Featuring ultrahigh sensitivity, wide detection range, and long‐term stability, the system leverages AI algorithms to decode spatiotemporal pressure signals, achieving accurate recognition of postoperative ...
Yingchun Li, Yarong Ding, Kaixin Lei, Yuze Zhang, Zhenhua Lin, Jiachun Sun, Kaitai Guo, Yang Zheng, Shaozhe Tan, Xuesi Zhang, Xinyue Li, Yue Hao, Xiangning Li, Yannan Liu, Jingjing Chang   +14 more
wiley   +1 more source

Time Course of Changes in Peripheral Blood Gene Expression During Medication Treatment for Major Depressive Disorder. [PDF]

, 2019
Changes in gene expression (GE) during antidepressant treatment may increase understanding of the action of antidepressant medications and serve as biomarkers of efficacy.
Congdon, Eliza, Cook, Ian A, Coppola, Giovanni, Hamilton, Steven P, Hunter, Aimee M, Krantz, David E, Leuchter, Andrew F   +6 more
core   +1 more source

Protein docking refinement by convex underestimation in the low-dimensional subspace of encounter complexes [PDF]

, 2018
We propose a novel stochastic global optimization algorithm with applications to the refinement stage of protein docking prediction methods. Our approach can process conformations sampled from multiple clusters, each roughly corresponding to a different ...
Kozakov, Dmytro, Li, Keyong, Moghadasi, Mohammad, Nan, Feng, Paschalidis, Ioannis Ch., Roshandelpoor, Athar, Vajda, Sandor, Vakili, Pirooz, Zarbafian, Shahrooz   +8 more
core   +2 more sources

DNA polymerase IV primarily operates outside of DNA replication forks in Escherichia coli

PLoS Genetics, 2018
In Escherichia coli, damage to the chromosomal DNA induces the SOS response, setting in motion a series of different DNA repair and damage tolerance pathways.
Sarah S. Henrikus, E. Wood, J. McDonald, M. Cox, R. Woodgate, M. Goodman, A. V. van Oijen, Andrew Robinson   +7 more
semanticscholar   +1 more source

The SOS response of Listeria monocytogenes is involved in stress resistance and mutagenesis [PDF]

The SOS response is a conserved pathway that is activated under certain stress conditions and is regulated by the repressor LexA and the activator RecA.
Abee, T., Molenaar, D., Schalkwijk, S., van, Veen, S., van der, Vos, W.M., de, Wells-Bennik, M.H.J.   +5 more
core   +1 more source

How Signals of Silence Sustain Sexual Harassment and What to Do About It

Human Resource Management, EarlyView.
ABSTRACT Sexual harassment has persisted for decades as an open secret within organizations, creating an ongoing challenge for Human Resource practitioners. Many employees experience or witness harassment yet say nothing. When they contemplate complaining, they are discouraged from doing so. Some still muster the courage to speak out about these abuses,
Angela L. Workman‐Stark, Zhanna Lyubykh, Ivana Vranjes, Lilia M. Cortina, M. Sandy Hershcovis, Jennifer L. Berdahl, Carla Chrusch   +6 more
wiley   +1 more source