Results 221 to 230 of about 4,059,453 (353)
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun +15 more
wiley +1 more source
Musical Ratios in Sounds from the Human Cochlea
Katarzyna J. Blinowska +3 more
openalex +2 more sources
Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai +13 more
wiley +1 more source
Numerical simulation study of the sonic detection and imaging methods for fish top in downhole environments. [PDF]
Hu Z, Yang D, Wu W, Gao X, Wang L.
europepmc +1 more source
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang +12 more
wiley +1 more source
Retrospective on decadal progress of the NOAA/NPS ocean noise reference station network. [PDF]
Haver SM +10 more
europepmc +1 more source
Phonological Processing Ability of Children with Speech Sound Disorders and Developmental Dyslexia in Early Elementary School Years [PDF]
Rayeon Lee, Seunghee Ha
openalex +1 more source
Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot +2 more
wiley +1 more source

